| SP | Scherzer, M.Scherzer, Max $ >> | 33 | 2017 | R | 95 | 35 | 35 | 9 | 14 | 4.27 | .314 | 1.36 | 7.9 | 4.4 | 9.4 | 225.1 | 197 | 114 | 107 | 33 | 110 | 234 | 0 | 0 | 0 | 0 | 17 | 2 | 5 | 4.32 |
| SP | Arrieta, J.Arrieta, Jake # $ >> | 29 | 2015 | R | 92 | 34 | 34 | 19 | 8 | 4.11 | .279 | 1.14 | 8.1 | 2.1 | 7.4 | 232.1 | 209 | 111 | 106 | 30 | 55 | 190 | 3 | 0 | 0 | 0 | 21 | 6 | 6 | 3.83 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 85 | 33 | 33 | 8 | 13 | 4.50 | .313 | 1.36 | 9.7 | 2.6 | 5.5 | 178.0 | 191 | 107 | 89 | 29 | 51 | 109 | 0 | 0 | 0 | 0 | 12 | 1 | 4 | 4.77 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 33 | 33 | 16 | 5 | 4.03 | .306 | 1.30 | 8.8 | 3.0 | 6.1 | 241.0 | 235 | 113 | 108 | 25 | 79 | 163 | 7 | 0 | 0 | 1 | 19 | 5 | 4 | 4.04 |
| CL | Adams, M.Adams, Mike † $ >> | 31 | 2009 | R | 99 | 71 | 0 | 4 | 8 | 2.70 | .296 | 1.22 | 7.0 | 4.1 | 10.4 | 66.2 | 51 | 20 | 20 | 4 | 30 | 76 | 0 | 41 | 1 | 0 | 0 | 3 | 1 | 2.98 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 93 | 77 | 0 | 10 | 5 | 3.54 | .292 | 1.21 | 7.1 | 3.8 | 9.1 | 89.0 | 70 | 42 | 35 | 5 | 38 | 90 | 0 | 0 | 5 | 0 | 0 | 2 | 2 | 3.06 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 79 | 0 | 5 | 10 | 4.26 | .320 | 1.38 | 7.3 | 5.2 | 8.5 | 99.1 | 80 | 51 | 47 | 12 | 57 | 93 | 0 | 1 | 8 | 0 | 0 | 3 | 1 | 4.52 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 67 | 0 | 8 | 2 | 3.29 | .296 | 1.23 | 6.2 | 5.0 | 7.8 | 65.2 | 45 | 24 | 24 | 6 | 36 | 56 | 0 | 4 | 4 | 0 | 0 | 2 | 0 | 4.23 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 44 | 0 | 5 | 1 | 1.64 | .237 | 0.91 | 3.9 | 4.3 | 8.6 | 44.0 | 19 | 8 | 8 | 2 | 21 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 3.18 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 1 | 0 | 0 | 0 | 6.75 | .429 | 2.25 | 27.0 | 0.0 | 0.0 | 1.1 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 16.00 |