| SP | Johnson, W.Johnson, Walter † >> | 26 | 1913 | R | 95 | 19 | 19 | 10 | 6 | 2.91 | .265 | 1.06 | 6.9 | 2.6 | 4.3 | 136.0 | 105 | 55 | 44 | 8 | 39 | 65 | 4 | 0 | 0 | 2 | 13 | 3 | 7 | 3.74 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 18 | 18 | 5 | 7 | 4.10 | .308 | 1.31 | 9.0 | 2.8 | 8.7 | 116.1 | 116 | 53 | 53 | 15 | 36 | 112 | 0 | 0 | 0 | 0 | 11 | 3 | 2 | 3.76 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 17 | 17 | 6 | 4 | 4.15 | .306 | 1.31 | 7.8 | 4.0 | 8.3 | 108.1 | 94 | 50 | 50 | 10 | 48 | 100 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 3.71 |
| CL | Feliz, N.Feliz, Neftali † $ >> | 21 | 2009 | R | 97 | 39 | 0 | 0 | 7 | 3.43 | .292 | 1.19 | 7.1 | 3.6 | 7.9 | 42.0 | 33 | 17 | 16 | 5 | 17 | 37 | 0 | 26 | 4 | 0 | 0 | 2 | 0 | 4.14 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 48 | 0 | 3 | 4 | 3.97 | .251 | 0.99 | 7.4 | 1.6 | 5.5 | 56.2 | 46 | 25 | 25 | 8 | 10 | 34 | 0 | 2 | 5 | 0 | 0 | 1 | 0 | 4.23 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 28 | 0 | 2 | 1 | 6.59 | .328 | 1.46 | 9.3 | 4.0 | 8.7 | 27.1 | 28 | 20 | 20 | 6 | 12 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.30 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 15 | 0 | 1 | 2 | 3.78 | .231 | 0.90 | 5.6 | 2.8 | 6.2 | 16.2 | 10 | 7 | 7 | 4 | 5 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.81 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 7 | 0 | 1 | 0 | 2.89 | .263 | 1.07 | 7.0 | 3.0 | 5.0 | 9.1 | 7 | 3 | 3 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.33 |