| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 23 | 23 | 8 | 9 | 4.88 | .308 | 1.31 | 9.4 | 2.5 | 5.4 | 153.0 | 159 | 83 | 83 | 25 | 42 | 92 | 3 | 0 | 0 | 0 | 11 | 3 | 3 | 4.80 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 22 | 22 | 8 | 10 | 3.86 | .319 | 1.39 | 8.0 | 4.5 | 4.7 | 135.1 | 120 | 66 | 58 | 7 | 68 | 70 | 0 | 0 | 0 | 0 | 13 | 2 | 0 | 4.19 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 21 | 21 | 6 | 7 | 5.83 | .329 | 1.44 | 10.1 | 2.9 | 4.4 | 126.2 | 141 | 89 | 82 | 26 | 41 | 62 | 1 | 0 | 0 | 0 | 10 | 4 | 3 | 5.77 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 20 | 20 | 10 | 8 | 3.83 | .291 | 1.22 | 8.1 | 2.9 | 6.1 | 138.2 | 124 | 61 | 59 | 13 | 45 | 93 | 5 | 0 | 0 | 1 | 12 | 2 | 1 | 3.90 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 93 | 35 | 0 | 3 | 4 | 2.97 | .331 | 1.43 | 6.8 | 6.3 | 9.3 | 36.1 | 27 | 14 | 12 | 2 | 25 | 37 | 0 | 18 | 3 | 0 | 0 | 2 | 3 | 3.92 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 48 | 0 | 2 | 3 | 4.14 | .302 | 1.26 | 8.5 | 2.9 | 9.5 | 58.2 | 55 | 32 | 27 | 10 | 19 | 61 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 4.22 |
| SU | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 34 | 0 | 2 | 3 | 5.22 | .328 | 1.47 | 7.1 | 6.2 | 8.1 | 29.1 | 23 | 20 | 17 | 4 | 20 | 26 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 5.07 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 43 | 0 | 1 | 1 | 3.98 | .322 | 1.43 | 9.5 | 3.6 | 9.0 | 40.2 | 42 | 19 | 18 | 4 | 16 | 40 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 26 | 0 | 0 | 2 | 1.62 | .220 | 0.85 | 4.6 | 3.0 | 6.2 | 39.0 | 20 | 7 | 7 | 3 | 13 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.62 |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 16 | 1 | 1 | 1 | 4.71 | .299 | 1.28 | 7.4 | 4.3 | 5.1 | 72.2 | 59 | 39 | 38 | 10 | 34 | 41 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.08 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 20 | 0 | 1 | 3 | 4.13 | .274 | 1.09 | 5.5 | 4.5 | 8.4 | 28.1 | 17 | 13 | 13 | 3 | 14 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.14 |