| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 23 | 23 | 9 | 7 | 4.12 | .300 | 1.28 | 7.5 | 4.0 | 8.9 | 153.0 | 128 | 73 | 70 | 19 | 68 | 151 | 1 | 0 | 0 | 1 | 13 | 1 | 4 | 3.99 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 22 | 22 | 10 | 6 | 4.34 | .303 | 1.29 | 8.9 | 2.6 | 7.1 | 170.0 | 169 | 87 | 82 | 25 | 50 | 135 | 5 | 0 | 0 | 1 | 10 | 3 | 1 | 4.26 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 21 | 21 | 6 | 12 | 6.64 | .369 | 1.73 | 11.8 | 3.7 | 4.0 | 137.0 | 180 | 109 | 101 | 19 | 57 | 61 | 6 | 0 | 0 | 0 | 7 | 3 | 5 | 5.23 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 21 | 21 | 8 | 5 | 5.60 | .374 | 1.76 | 8.8 | 7.1 | 8.7 | 117.1 | 115 | 77 | 73 | 10 | 92 | 113 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.62 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 21 | 21 | 5 | 7 | 4.40 | .348 | 1.57 | 8.7 | 5.5 | 4.6 | 122.2 | 118 | 67 | 60 | 11 | 74 | 63 | 0 | 0 | 0 | 0 | 13 | 4 | 9 | 5.06 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 94 | 54 | 0 | 2 | 2 | 3.44 | .318 | 1.40 | 7.3 | 5.3 | 8.3 | 68.0 | 55 | 26 | 26 | 7 | 40 | 63 | 0 | 4 | 3 | 0 | 0 | 0 | 3 | 4.25 |
| RP | Bautista, F.Bautista, Félix # >> | 28 | 2023 | R | 74 | 52 | 0 | 4 | 4 | 5.43 | .338 | 1.53 | 8.1 | 5.8 | 11.4 | 61.1 | 55 | 41 | 37 | 3 | 39 | 77 | 0 | 4 | 5 | 0 | 0 | 0 | 3 | 3.03 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 47 | 0 | 6 | 2 | 5.29 | .330 | 1.46 | 8.6 | 4.6 | 10.8 | 49.1 | 47 | 34 | 29 | 4 | 25 | 59 | 0 | 9 | 2 | 0 | 0 | 1 | 1 | 3.24 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 36 | 0 | 4 | 5 | 7.13 | .343 | 1.55 | 9.2 | 4.8 | 8.8 | 53.0 | 54 | 45 | 42 | 15 | 28 | 52 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 6.36 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 16 | 0 | 2 | 1 | 5.54 | .355 | 1.65 | 9.3 | 5.5 | 6.9 | 26.0 | 27 | 19 | 16 | 3 | 16 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.81 |