| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 19 | 19 | 4 | 9 | 4.72 | .297 | 1.20 | 8.4 | 2.5 | 8.1 | 110.2 | 103 | 62 | 58 | 13 | 30 | 99 | 3 | 0 | 0 | 0 | 10 | 7 | 2 | 3.75 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 17 | 17 | 6 | 9 | 4.79 | .333 | 1.47 | 9.8 | 3.4 | 4.7 | 107.0 | 117 | 61 | 57 | 14 | 40 | 56 | 2 | 0 | 0 | 0 | 9 | 3 | 2 | 4.86 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 16 | 16 | 3 | 5 | 5.17 | .351 | 1.59 | 9.9 | 4.3 | 6.2 | 87.0 | 96 | 51 | 50 | 12 | 42 | 60 | 1 | 0 | 0 | 0 | 7 | 3 | 1 | 4.97 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 44 | 0 | 1 | 3 | 5.08 | .277 | 1.15 | 8.8 | 1.6 | 7.1 | 51.1 | 50 | 29 | 29 | 4 | 9 | 40 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2.98 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 35 | 0 | 1 | 1 | 3.82 | .340 | 1.55 | 9.0 | 4.9 | 8.7 | 33.0 | 33 | 14 | 14 | 4 | 18 | 32 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.27 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 31 | 0 | 3 | 1 | 6.86 | .376 | 1.81 | 12.2 | 4.2 | 5.8 | 39.1 | 53 | 32 | 30 | 6 | 18 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 5.10 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 31 | 0 | 4 | 3 | 3.43 | .306 | 1.25 | 6.7 | 4.6 | 6.5 | 39.1 | 29 | 16 | 15 | 4 | 20 | 28 | 0 | 11 | 3 | 0 | 0 | 3 | 1 | 4.67 |