| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 34 | 34 | 14 | 11 | 4.12 | .301 | 1.28 | 8.0 | 3.5 | 7.3 | 214.0 | 190 | 99 | 98 | 23 | 83 | 173 | 2 | 0 | 0 | 0 | 18 | 3 | 5 | 3.99 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 33 | 33 | 9 | 17 | 5.73 | .337 | 1.50 | 10.7 | 2.9 | 8.8 | 180.2 | 214 | 121 | 115 | 31 | 57 | 176 | 1 | 0 | 0 | 0 | 14 | 4 | 4 | 4.30 |
| SP | Brown, M.Brown, Mordecai $ >> | 32 | 1908 | R | 84 | 31 | 31 | 11 | 13 | 4.49 | .319 | 1.38 | 9.8 | 2.7 | 4.0 | 188.1 | 204 | 104 | 94 | 18 | 56 | 84 | 3 | 0 | 0 | 1 | 16 | 5 | 9 | 4.32 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 32 | 32 | 8 | 14 | 7.80 | .389 | 1.91 | 10.8 | 6.4 | 8.5 | 137.1 | 165 | 126 | 119 | 27 | 97 | 129 | 0 | 0 | 0 | 0 | 7 | 0 | 4 | 5.80 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 76 | 0 | 4 | 3 | 3.75 | .311 | 1.33 | 9.4 | 2.7 | 8.4 | 98.1 | 102 | 47 | 41 | 10 | 29 | 91 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.42 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 66 | 0 | 4 | 1 | 4.15 | .305 | 1.29 | 8.1 | 3.6 | 7.4 | 80.1 | 72 | 40 | 37 | 12 | 32 | 66 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 4.58 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 56 | 0 | 2 | 2 | 4.54 | .293 | 1.24 | 8.5 | 2.7 | 8.7 | 69.1 | 65 | 35 | 35 | 10 | 21 | 67 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 3.86 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 52 | 0 | 3 | 0 | 6.18 | .349 | 1.58 | 7.7 | 6.7 | 8.7 | 62.2 | 53 | 44 | 43 | 11 | 46 | 60 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.69 |
| SU | Rivera, M.Rivera, Mariano $$ >> | 39 | 2008 | R | 85 | 59 | 0 | 0 | 3 | 5.17 | .326 | 1.40 | 9.9 | 2.9 | 8.9 | 62.2 | 68 | 36 | 36 | 8 | 20 | 61 | 0 | 5 | 2 | 0 | 0 | 3 | 1 | 3.82 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 58 | 0 | 5 | 8 | 4.34 | .332 | 1.48 | 8.7 | 4.6 | 10.9 | 66.1 | 64 | 32 | 32 | 7 | 34 | 80 | 0 | 24 | 7 | 0 | 0 | 1 | 5 | 3.55 |