| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 93 | 19 | 19 | 8 | 5 | 3.80 | .296 | 1.22 | 7.4 | 3.6 | 6.7 | 116.0 | 96 | 49 | 49 | 13 | 46 | 86 | 0 | 0 | 0 | 0 | 11 | 4 | 2 | 4.27 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 18 | 18 | 8 | 7 | 4.39 | .308 | 1.33 | 8.2 | 3.8 | 8.2 | 110.2 | 100 | 60 | 54 | 17 | 47 | 100 | 1 | 0 | 0 | 0 | 10 | 1 | 0 | 4.50 |
| SP | Mathewson, C.Mathewson, Christy † >> | 29 | 1909 | R | 85 | 18 | 18 | 11 | 2 | 2.93 | .262 | 1.03 | 7.0 | 2.3 | 3.9 | 116.2 | 90 | 38 | 38 | 7 | 30 | 50 | 4 | 0 | 0 | 2 | 12 | 4 | 2 | 3.80 |
| SP | Carlton, S.Carlton, Steve † >> | 28 | 1972 | L | 51 | 17 | 17 | 13 | 3 | 2.10 | .257 | 1.03 | 6.8 | 2.5 | 5.5 | 132.2 | 99 | 35 | 31 | 3 | 37 | 81 | 4 | 0 | 0 | 0 | 15 | 2 | 4 | 2.95 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 39 | 16 | 16 | 7 | 5 | 4.66 | .305 | 1.29 | 8.1 | 3.5 | 7.2 | 100.1 | 90 | 54 | 52 | 14 | 39 | 80 | 1 | 0 | 0 | 1 | 6 | 3 | 3 | 4.48 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 40 | 0 | 4 | 2 | 1.89 | .245 | 0.97 | 6.1 | 2.8 | 10.6 | 52.1 | 35 | 11 | 11 | 3 | 16 | 61 | 0 | 12 | 0 | 0 | 0 | 0 | 1 | 2.33 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 21 | 0 | 5 | 1 | 3.04 | .304 | 1.27 | 7.4 | 4.3 | 9.8 | 23.2 | 19 | 8 | 8 | 0 | 11 | 25 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 2.39 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 17 | 0 | 1 | 1 | 6.00 | .408 | 2.07 | 10.8 | 7.8 | 7.8 | 15.0 | 18 | 10 | 10 | 0 | 13 | 13 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 3.87 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 5 | 0 | 0 | 0 | 13.50 | .500 | 3.00 | 15.8 | 11.3 | 9.0 | 4.0 | 7 | 6 | 6 | 2 | 5 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.25 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 22 | 0 | 3 | 0 | 3.31 | .250 | 0.96 | 6.1 | 2.6 | 8.1 | 49.0 | 33 | 18 | 18 | 5 | 14 | 44 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.51 |