| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 30 | 30 | 12 | 7 | 4.58 | .306 | 1.29 | 8.3 | 3.4 | 5.4 | 176.2 | 162 | 97 | 90 | 19 | 66 | 106 | 1 | 0 | 0 | 0 | 18 | 6 | 3 | 4.43 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 30 | 30 | 16 | 5 | 3.45 | .277 | 1.14 | 7.9 | 2.3 | 3.9 | 213.2 | 188 | 85 | 82 | 22 | 55 | 93 | 5 | 0 | 0 | 0 | 19 | 3 | 5 | 4.29 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 30 | 30 | 10 | 10 | 4.45 | .300 | 1.26 | 8.3 | 3.1 | 7.5 | 192.1 | 176 | 105 | 95 | 29 | 67 | 160 | 4 | 0 | 0 | 1 | 15 | 4 | 3 | 4.41 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 29 | 29 | 10 | 7 | 5.93 | .333 | 1.48 | 10.4 | 3.0 | 5.2 | 151.2 | 174 | 100 | 100 | 29 | 51 | 87 | 3 | 0 | 0 | 1 | 10 | 2 | 4 | 5.40 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 80 | 0 | 7 | 10 | 3.90 | .299 | 1.25 | 8.0 | 3.4 | 9.1 | 87.2 | 77 | 43 | 38 | 9 | 33 | 88 | 0 | 31 | 8 | 0 | 0 | 2 | 2 | 3.53 |
| SU | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 88 | 0 | 8 | 4 | 2.53 | .258 | 1.02 | 6.9 | 2.3 | 9.0 | 103.1 | 79 | 30 | 29 | 11 | 26 | 103 | 0 | 3 | 7 | 0 | 0 | 3 | 1 | 3.23 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 96 | 0 | 5 | 4 | 4.41 | .297 | 1.26 | 8.4 | 3.0 | 8.0 | 102.0 | 95 | 51 | 50 | 21 | 34 | 91 | 0 | 4 | 4 | 0 | 0 | 0 | 3 | 4.89 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 72 | 0 | 5 | 1 | 3.95 | .305 | 1.30 | 8.3 | 3.4 | 8.1 | 82.0 | 76 | 36 | 36 | 12 | 31 | 74 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 4.27 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 74 | 52 | 0 | 7 | 1 | 4.14 | .324 | 1.44 | 8.6 | 4.4 | 9.1 | 67.1 | 64 | 34 | 31 | 14 | 33 | 68 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.16 |