| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 19 | 19 | 7 | 5 | 5.40 | .324 | 1.40 | 9.3 | 3.4 | 8.7 | 101.2 | 104 | 63 | 61 | 12 | 38 | 98 | 0 | 0 | 0 | 0 | 10 | 4 | 0 | 3.85 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 18 | 18 | 7 | 6 | 5.05 | .338 | 1.51 | 10.4 | 3.3 | 10.5 | 101.2 | 117 | 57 | 57 | 16 | 37 | 118 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 3.88 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 18 | 17 | 1 | 10 | 6.80 | .374 | 1.76 | 11.2 | 4.6 | 5.1 | 90.0 | 112 | 79 | 68 | 15 | 46 | 51 | 2 | 0 | 0 | 0 | 4 | 3 | 4 | 5.67 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 46 | 0 | 7 | 3 | 3.42 | .288 | 1.20 | 7.3 | 3.6 | 10.0 | 52.2 | 42 | 20 | 20 | 2 | 21 | 58 | 0 | 12 | 1 | 0 | 0 | 1 | 1 | 2.54 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 53 | 0 | 3 | 0 | 5.30 | .332 | 1.47 | 11.3 | 2.0 | 8.8 | 54.1 | 68 | 34 | 32 | 12 | 12 | 53 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.65 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 42 | 0 | 2 | 0 | 4.61 | .325 | 1.44 | 9.5 | 3.6 | 8.1 | 52.2 | 55 | 29 | 27 | 4 | 21 | 47 | 0 | 3 | 2 | 0 | 0 | 0 | 3 | 3.40 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 42 | 0 | 1 | 1 | 4.27 | .305 | 1.32 | 8.8 | 3.1 | 8.4 | 46.1 | 45 | 24 | 22 | 11 | 16 | 43 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.28 |