| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 31 | 31 | 17 | 8 | 3.89 | .291 | 1.21 | 8.5 | 2.4 | 4.6 | 231.1 | 217 | 106 | 100 | 25 | 62 | 119 | 11 | 0 | 0 | 0 | 16 | 6 | 4 | 4.26 |
| SP | Alexander, P.Alexander, Pete # >> | 28 | 1915 | R | 88 | 30 | 30 | 13 | 11 | 3.74 | .277 | 1.13 | 8.3 | 1.9 | 4.9 | 231.0 | 212 | 105 | 96 | 20 | 49 | 126 | 10 | 0 | 0 | 2 | 15 | 5 | 3 | 3.74 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 29 | 29 | 9 | 11 | 5.91 | .351 | 1.60 | 10.4 | 4.0 | 6.1 | 179.2 | 207 | 130 | 118 | 28 | 80 | 122 | 2 | 0 | 0 | 0 | 11 | 5 | 3 | 5.09 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 29 | 29 | 11 | 13 | 4.84 | .334 | 1.49 | 9.4 | 4.1 | 4.4 | 200.2 | 209 | 114 | 108 | 23 | 90 | 97 | 9 | 0 | 0 | 0 | 12 | 3 | 5 | 4.92 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 28 | 28 | 7 | 18 | 5.68 | .353 | 1.60 | 10.5 | 3.9 | 5.6 | 172.2 | 201 | 117 | 109 | 16 | 75 | 107 | 2 | 0 | 0 | 0 | 10 | 6 | 6 | 4.38 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 70 | 0 | 3 | 4 | 2.64 | .257 | 1.04 | 6.4 | 2.9 | 10.2 | 95.1 | 68 | 29 | 28 | 10 | 31 | 108 | 0 | 7 | 2 | 0 | 0 | 0 | 3 | 3.07 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 56 | 0 | 2 | 3 | 2.97 | .318 | 1.38 | 7.1 | 5.4 | 8.1 | 63.2 | 50 | 21 | 21 | 5 | 38 | 57 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 4.08 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 51 | 0 | 0 | 3 | 4.77 | .327 | 1.44 | 11.1 | 2.0 | 8.3 | 60.1 | 74 | 36 | 32 | 10 | 13 | 55 | 0 | 6 | 0 | 0 | 0 | 1 | 1 | 4.03 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 1 | 1 | 0 | 4.05 | .286 | 1.20 | 6.0 | 6.0 | 3.0 | 6.2 | 4 | 3 | 3 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.33 |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 2 | 0 | 0 | 0 | 8.10 | .500 | 3.00 | 18.0 | 12.0 | 6.0 | 3.1 | 6 | 3 | 3 | 1 | 4 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 10.00 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 0 | 0 | 0 | 0.00 | .500 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | - |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 25 | 0 | 2 | 4 | 7.19 | .337 | 1.52 | 9.7 | 4.2 | 6.1 | 41.1 | 44 | 33 | 33 | 12 | 19 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.83 |