| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 15 | 13 | 3.84 | .293 | 1.23 | 7.7 | 3.4 | 8.5 | 241.2 | 206 | 111 | 103 | 29 | 91 | 228 | 3 | 0 | 0 | 0 | 21 | 3 | 2 | 3.84 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 32 | 32 | 9 | 16 | 4.93 | .329 | 1.45 | 9.2 | 3.8 | 4.6 | 197.0 | 201 | 119 | 108 | 25 | 84 | 101 | 0 | 0 | 0 | 0 | 15 | 5 | 1 | 4.98 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 31 | 31 | 10 | 17 | 4.47 | .303 | 1.29 | 8.8 | 2.8 | 3.9 | 237.1 | 232 | 132 | 118 | 32 | 73 | 104 | 14 | 0 | 0 | 2 | 10 | 4 | 7 | 4.85 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 64 | 31 | 31 | 13 | 11 | 4.51 | .310 | 1.33 | 9.4 | 2.6 | 4.6 | 223.2 | 232 | 123 | 112 | 22 | 65 | 114 | 7 | 0 | 0 | 3 | 15 | 4 | 3 | 4.19 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 85 | 0 | 6 | 2 | 3.32 | .300 | 1.25 | 6.9 | 4.4 | 8.7 | 130.0 | 100 | 50 | 48 | 18 | 63 | 125 | 0 | 10 | 4 | 0 | 0 | 4 | 0 | 4.42 |
| RP | Hoffman, T.Hoffman, Trevor † >> | 31 | 1998 | R | 75 | 71 | 0 | 9 | 4 | 2.90 | .272 | 1.10 | 6.7 | 3.2 | 7.9 | 93.0 | 69 | 32 | 30 | 7 | 33 | 82 | 0 | 7 | 5 | 0 | 0 | 2 | 7 | 3.34 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 1 | 1 | 1 | 0 | 9.95 | .441 | 2.37 | 18.0 | 4.5 | 3.0 | 6.1 | 12 | 7 | 7 | 1 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.00 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 1 | 0 | 0 | 0 | 0.00 | .400 | 2.00 | 9.0 | 9.0 | 0.0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |