| SP | Young, C.Young, Cy † # >> | 41 | 1908 | R | 66 | 28 | 28 | 18 | 8 | 3.78 | .283 | 1.18 | 8.4 | 2.2 | 4.5 | 223.2 | 209 | 103 | 94 | 35 | 55 | 111 | 19 | 0 | 0 | 1 | 13 | 1 | 5 | 4.80 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 28 | 28 | 11 | 14 | 4.45 | .323 | 1.40 | 8.8 | 3.8 | 4.6 | 206.1 | 201 | 108 | 102 | 28 | 88 | 105 | 9 | 0 | 0 | 2 | 14 | 6 | 8 | 5.12 |
| RP | Lidge, B.Lidge, Brad # >> | 28 | 2004 | R | 64 | 39 | 0 | 1 | 3 | 5.95 | .332 | 1.44 | 9.2 | 3.9 | 9.0 | 42.1 | 43 | 28 | 28 | 6 | 18 | 42 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 4.29 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 37 | 0 | 1 | 3 | 3.51 | .322 | 1.43 | 6.7 | 6.3 | 5.7 | 66.2 | 49 | 28 | 26 | 6 | 46 | 42 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.00 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 3 | 3 | 0 | 3 | 7.59 | .379 | 1.78 | 10.3 | 6.0 | 3.0 | 21.1 | 24 | 18 | 18 | 4 | 14 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 6.95 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 3 | 0 | 0 | 2 | 7.71 | .462 | 2.57 | 18.0 | 9.0 | 4.5 | 2.1 | 4 | 2 | 2 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 11.50 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 14 | 0 | 1 | 1 | 3.47 | .327 | 1.46 | 9.4 | 3.9 | 8.6 | 23.1 | 24 | 9 | 9 | 3 | 10 | 22 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 4.09 |