| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 30 | 30 | 13 | 12 | 3.43 | .284 | 1.17 | 8.2 | 2.4 | 8.2 | 225.2 | 204 | 96 | 86 | 27 | 61 | 206 | 3 | 0 | 0 | 2 | 19 | 3 | 4 | 3.58 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 30 | 30 | 10 | 10 | 4.66 | .295 | 1.24 | 9.2 | 2.0 | 4.7 | 164.0 | 167 | 95 | 85 | 30 | 37 | 86 | 0 | 0 | 0 | 0 | 11 | 2 | 2 | 5.04 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 29 | 29 | 9 | 14 | 5.42 | .334 | 1.48 | 10.5 | 2.8 | 5.4 | 201.0 | 234 | 122 | 121 | 30 | 63 | 120 | 3 | 0 | 0 | 0 | 10 | 5 | 2 | 4.76 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 29 | 29 | 7 | 16 | 5.89 | .355 | 1.64 | 10.9 | 3.9 | 6.4 | 186.1 | 225 | 131 | 122 | 27 | 80 | 133 | 6 | 0 | 0 | 1 | 10 | 3 | 4 | 4.80 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 64 | 28 | 28 | 10 | 10 | 4.69 | .310 | 1.34 | 9.4 | 2.7 | 4.8 | 193.2 | 202 | 109 | 101 | 32 | 57 | 102 | 5 | 0 | 0 | 1 | 11 | 2 | 3 | 5.02 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 80 | 0 | 2 | 1 | 2.27 | .271 | 1.07 | 5.6 | 4.0 | 9.9 | 103.0 | 64 | 28 | 26 | 7 | 46 | 113 | 0 | 7 | 2 | 0 | 0 | 5 | 4 | 3.17 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 62 | 0 | 6 | 8 | 4.00 | .284 | 1.18 | 8.6 | 2.1 | 7.2 | 83.1 | 79 | 39 | 37 | 10 | 19 | 66 | 0 | 7 | 5 | 0 | 0 | 1 | 1 | 3.70 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 54 | 0 | 3 | 4 | 3.86 | .305 | 1.32 | 8.4 | 3.4 | 5.6 | 63.0 | 59 | 29 | 27 | 13 | 24 | 39 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 5.59 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 3 | 0 | 1 | 0 | 1.69 | .304 | 1.31 | 9.0 | 3.6 | 3.6 | 5.1 | 5 | 2 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.40 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 21 | 0 | 4 | 1 | 3.79 | .318 | 1.40 | 7.5 | 5.4 | 4.6 | 35.2 | 29 | 15 | 15 | 3 | 21 | 18 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.89 |