| SP | Martinez, P.Martinez, Pedro † # >> | 29 | 2000 | R | 100 | 36 | 36 | 22 | 9 | 2.66 | .243 | 0.95 | 6.3 | 2.2 | 7.9 | 287.1 | 202 | 88 | 85 | 22 | 71 | 253 | 14 | 0 | 0 | 6 | 27 | 4 | 3 | 3.02 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 34 | 34 | 17 | 13 | 3.34 | .265 | 1.06 | 7.2 | 2.3 | 5.2 | 253.0 | 202 | 97 | 94 | 28 | 65 | 147 | 9 | 0 | 0 | 3 | 20 | 7 | 6 | 4.13 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 33 | 33 | 14 | 12 | 5.04 | .311 | 1.35 | 9.5 | 2.6 | 6.5 | 219.2 | 232 | 127 | 123 | 32 | 64 | 157 | 7 | 0 | 0 | 1 | 15 | 2 | 10 | 4.37 |
| SP | McLain, D.McLain, Denny † >> | 24 | 1968 | R | 78 | 31 | 31 | 15 | 12 | 3.90 | .282 | 1.16 | 7.5 | 3.0 | 5.3 | 235.2 | 196 | 103 | 102 | 19 | 78 | 138 | 16 | 0 | 0 | 2 | 16 | 4 | 3 | 3.92 |
| RP | Doolittle, S.Doolittle, Sean $$ >> | 31 | 2018 | L | 99 | 79 | 0 | 4 | 1 | 2.17 | .245 | 0.94 | 6.6 | 1.9 | 9.6 | 108.0 | 79 | 26 | 26 | 9 | 23 | 115 | 0 | 12 | 2 | 0 | 0 | 3 | 0 | 2.68 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 68 | 0 | 3 | 5 | 3.72 | .295 | 1.24 | 7.8 | 3.5 | 8.1 | 67.2 | 58 | 29 | 28 | 8 | 26 | 60 | 0 | 10 | 3 | 0 | 0 | 1 | 3 | 3.97 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 37 | 0 | 4 | 1 | 2.20 | .205 | 0.78 | 5.7 | 1.3 | 7.7 | 49.0 | 31 | 12 | 12 | 4 | 7 | 42 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.78 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 26 | 0 | 2 | 2 | 3.78 | .301 | 1.26 | 8.2 | 3.3 | 9.0 | 33.1 | 30 | 14 | 14 | 1 | 12 | 33 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.58 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 25 | 0 | 2 | 2 | 3.44 | .239 | 0.91 | 5.3 | 2.9 | 7.4 | 34.0 | 20 | 13 | 13 | 4 | 11 | 28 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.94 |