| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 31 | 31 | 13 | 6 | 2.79 | .256 | 1.02 | 6.9 | 2.2 | 8.9 | 193.2 | 149 | 65 | 60 | 23 | 48 | 190 | 0 | 0 | 0 | 0 | 21 | 3 | 0 | 3.37 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 83 | 31 | 30 | 17 | 7 | 3.68 | .278 | 1.13 | 8.0 | 2.2 | 7.6 | 193.1 | 171 | 81 | 79 | 21 | 47 | 164 | 3 | 0 | 0 | 1 | 18 | 5 | 4 | 3.52 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 29 | 29 | 12 | 9 | 4.65 | .350 | 1.60 | 8.0 | 6.5 | 7.4 | 164.2 | 145 | 92 | 85 | 14 | 118 | 134 | 0 | 0 | 0 | 0 | 16 | 3 | 3 | 4.69 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 81 | 0 | 9 | 5 | 3.68 | .303 | 1.30 | 7.5 | 4.2 | 8.3 | 100.1 | 83 | 43 | 41 | 9 | 47 | 92 | 0 | 2 | 4 | 0 | 0 | 1 | 3 | 3.77 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 67 | 0 | 7 | 5 | 3.40 | .312 | 1.33 | 8.7 | 3.4 | 8.4 | 84.2 | 81 | 32 | 32 | 8 | 32 | 78 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 3.60 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 52 | 0 | 3 | 2 | 3.07 | .337 | 1.53 | 8.8 | 5.1 | 7.7 | 55.2 | 54 | 24 | 19 | 4 | 31 | 47 | 0 | 4 | 4 | 0 | 0 | 0 | 2 | 3.93 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 19 | 0 | 6 | 2 | 3.81 | .316 | 1.38 | 8.0 | 4.6 | 5.4 | 89.2 | 79 | 40 | 38 | 6 | 45 | 53 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.20 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 68 | 0 | 3 | 6 | 2.86 | .280 | 1.14 | 6.4 | 3.9 | 9.4 | 69.1 | 49 | 23 | 22 | 4 | 30 | 72 | 0 | 36 | 5 | 0 | 0 | 2 | 0 | 3.06 |