| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 33 | 33 | 11 | 14 | 4.19 | .309 | 1.32 | 9.5 | 2.4 | 9.0 | 193.1 | 203 | 94 | 90 | 25 | 52 | 193 | 0 | 0 | 0 | 0 | 15 | 4 | 0 | 3.55 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 9 | 13 | 5.82 | .346 | 1.58 | 10.3 | 3.9 | 5.3 | 182.1 | 209 | 128 | 118 | 30 | 79 | 107 | 3 | 0 | 0 | 0 | 12 | 2 | 1 | 5.30 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 32 | 32 | 10 | 14 | 5.71 | .319 | 1.39 | 9.5 | 3.1 | 9.6 | 157.2 | 165 | 108 | 100 | 35 | 54 | 167 | 0 | 0 | 0 | 0 | 11 | 3 | 3 | 4.86 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 73 | 31 | 31 | 9 | 11 | 4.27 | .329 | 1.43 | 9.9 | 3.1 | 4.5 | 191.2 | 210 | 111 | 91 | 22 | 65 | 96 | 4 | 0 | 0 | 1 | 16 | 7 | 2 | 4.62 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 76 | 0 | 3 | 7 | 4.77 | .342 | 1.53 | 9.5 | 4.4 | 8.6 | 88.2 | 93 | 49 | 47 | 12 | 43 | 84 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.40 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 65 | 0 | 5 | 3 | 4.14 | .327 | 1.42 | 8.1 | 4.6 | 7.4 | 74.0 | 67 | 40 | 34 | 7 | 38 | 61 | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 4.24 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 57 | 0 | 2 | 2 | 5.06 | .353 | 1.61 | 10.0 | 4.5 | 5.2 | 117.1 | 130 | 72 | 66 | 15 | 59 | 67 | 0 | 0 | 1 | 0 | 0 | 3 | 7 | 5.11 |
| CL | Uehara, K.Uehara, Koji $$ >> | 38 | 2013 | R | 100 | 50 | 0 | 2 | 3 | 2.77 | .278 | 1.15 | 6.9 | 3.5 | 10.4 | 52.0 | 40 | 20 | 16 | 3 | 20 | 60 | 0 | 28 | 2 | 0 | 0 | 0 | 0 | 2.60 |