| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 4 | 4 | 0 | 2 | 8.22 | .395 | 1.91 | 13.7 | 3.5 | 9.4 | 23.0 | 35 | 22 | 21 | 9 | 9 | 24 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 7.30 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 4 | 4 | 1 | 2 | 6.53 | .347 | 1.60 | 11.7 | 3.2 | 5.0 | 20.2 | 26 | 16 | 15 | 5 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.20 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 4 | 4 | 1 | 3 | 4.22 | .309 | 1.31 | 7.9 | 3.9 | 6.2 | 32.0 | 28 | 15 | 15 | 5 | 14 | 22 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.06 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 8 | 0 | 0 | 0 | 3.48 | .244 | 0.97 | 6.3 | 2.7 | 7.2 | 10.1 | 7 | 4 | 4 | 1 | 3 | 8 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.60 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 10 | 0 | 1 | 1 | 1.35 | .310 | 1.35 | 8.3 | 4.2 | 12.5 | 13.1 | 12 | 8 | 2 | 2 | 6 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.62 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 11 | 0 | 3 | 1 | 8.10 | .375 | 1.80 | 13.5 | 2.7 | 9.0 | 10.0 | 15 | 9 | 9 | 3 | 3 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.80 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 10 | 0 | 0 | 0 | 4.50 | .288 | 1.21 | 7.7 | 3.2 | 7.1 | 14.0 | 12 | 7 | 7 | 2 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.36 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 10 | 0 | 1 | 0 | 7.88 | .250 | 1.00 | 7.9 | 1.1 | 12.4 | 8.0 | 7 | 7 | 7 | 2 | 1 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.88 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 4 | 0 | 0 | 1 | 2.25 | .200 | 0.75 | 4.5 | 2.3 | 4.5 | 4.0 | 2 | 1 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |