| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 32 | 32 | 14 | 13 | 3.51 | .296 | 1.24 | 8.6 | 2.6 | 8.7 | 241.1 | 229 | 97 | 94 | 27 | 70 | 233 | 5 | 0 | 0 | 0 | 20 | 6 | 3 | 3.47 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 31 | 31 | 12 | 14 | 4.74 | .311 | 1.31 | 8.6 | 3.3 | 5.2 | 229.2 | 218 | 127 | 121 | 25 | 84 | 132 | 11 | 0 | 0 | 4 | 12 | 9 | 4 | 4.48 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 70 | 0 | 3 | 5 | 4.40 | .297 | 1.22 | 8.1 | 2.9 | 7.7 | 94.0 | 85 | 46 | 46 | 14 | 30 | 80 | 0 | 9 | 2 | 0 | 0 | 4 | 0 | 4.32 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 58 | 0 | 4 | 5 | 3.66 | .301 | 1.29 | 7.7 | 3.9 | 5.0 | 96.0 | 82 | 40 | 39 | 10 | 42 | 53 | 0 | 10 | 3 | 0 | 0 | 0 | 5 | 4.56 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 37 | 0 | 4 | 2 | 5.30 | .367 | 1.74 | 10.8 | 5.1 | 5.4 | 35.2 | 42 | 21 | 21 | 4 | 20 | 21 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 32 | 0 | 0 | 0 | 4.19 | .348 | 1.58 | 10.7 | 3.8 | 9.2 | 38.2 | 45 | 18 | 18 | 7 | 16 | 39 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.68 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 9 | 0 | 1 | 2 | 5.40 | .295 | 1.25 | 8.0 | 3.5 | 7.0 | 18.1 | 16 | 11 | 11 | 4 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.50 |