| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 32 | 32 | 11 | 14 | 3.88 | .280 | 1.14 | 7.5 | 2.8 | 7.6 | 225.0 | 188 | 99 | 97 | 29 | 69 | 190 | 3 | 0 | 0 | 0 | 19 | 6 | 4 | 3.99 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 30 | 30 | 10 | 16 | 4.61 | .308 | 1.31 | 9.3 | 2.5 | 4.8 | 226.2 | 234 | 120 | 116 | 20 | 62 | 120 | 15 | 0 | 0 | 1 | 13 | 7 | 5 | 4.00 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 81 | 0 | 9 | 5 | 4.11 | .312 | 1.33 | 7.0 | 5.1 | 9.5 | 111.2 | 86 | 59 | 51 | 10 | 63 | 117 | 0 | 3 | 3 | 0 | 0 | 3 | 3 | 3.85 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 69 | 0 | 2 | 2 | 3.19 | .299 | 1.25 | 6.6 | 4.7 | 8.8 | 87.1 | 64 | 35 | 31 | 11 | 45 | 85 | 0 | 5 | 4 | 0 | 0 | 3 | 5 | 4.34 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 61 | 0 | 1 | 3 | 5.20 | .308 | 1.33 | 6.6 | 5.5 | 8.3 | 72.2 | 53 | 43 | 42 | 10 | 44 | 66 | 0 | 8 | 2 | 0 | 0 | 0 | 1 | 4.81 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 58 | 0 | 1 | 4 | 5.21 | .342 | 1.56 | 9.0 | 5.1 | 8.2 | 57.0 | 57 | 33 | 33 | 7 | 32 | 52 | 0 | 7 | 0 | 0 | 0 | 0 | 7 | 4.46 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 1 | 0 | 0 | 0 | 13.50 | .500 | 3.00 | - | - | - | 0.2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 33 | 0 | 4 | 8 | 5.07 | .356 | 1.62 | 11.0 | 3.8 | 9.3 | 60.1 | 73 | 35 | 34 | 11 | 25 | 62 | 0 | 1 | 2 | 0 | 0 | 2 | 7 | 4.67 |