| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 32 | 32 | 20 | 9 | 3.79 | .285 | 1.17 | 8.5 | 2.0 | 7.8 | 233.0 | 220 | 100 | 98 | 24 | 52 | 201 | 6 | 0 | 0 | 2 | 20 | 7 | 6 | 3.37 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 31 | 31 | 12 | 14 | 4.16 | .295 | 1.23 | 8.2 | 2.9 | 7.7 | 218.2 | 199 | 105 | 101 | 22 | 71 | 186 | 1 | 0 | 0 | 0 | 16 | 4 | 3 | 3.64 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 30 | 30 | 13 | 7 | 3.03 | .267 | 1.07 | 7.1 | 2.5 | 5.3 | 232.0 | 183 | 83 | 78 | 18 | 65 | 136 | 9 | 0 | 0 | 2 | 20 | 5 | 3 | 3.74 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 30 | 30 | 14 | 10 | 3.82 | .305 | 1.28 | 6.8 | 4.7 | 8.0 | 190.2 | 144 | 83 | 81 | 21 | 100 | 169 | 2 | 0 | 0 | 1 | 18 | 7 | 2 | 4.35 |
| SP | Marichal, J.Marichal, Juan # >> | 28 | 1965 | R | 71 | 29 | 29 | 9 | 14 | 4.43 | .307 | 1.28 | 8.7 | 2.8 | 5.9 | 207.1 | 200 | 106 | 102 | 30 | 65 | 136 | 5 | 0 | 0 | 0 | 14 | 10 | 4 | 4.66 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 73 | 0 | 5 | 3 | 1.73 | .270 | 1.09 | 5.9 | 4.0 | 10.0 | 104.1 | 68 | 20 | 20 | 5 | 46 | 115 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 2.80 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 16 | 0 | 2 | 1 | 2.20 | .279 | 1.16 | 7.3 | 3.4 | 6.8 | 16.1 | 13 | 4 | 4 | 0 | 6 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.63 |
| CL | Diaz, E.Diaz, Edwin † $ >> | 24 | 2018 | R | 88 | 46 | 0 | 0 | 2 | 3.61 | .298 | 1.25 | 8.1 | 3.2 | 8.8 | 42.1 | 38 | 18 | 17 | 3 | 15 | 41 | 0 | 36 | 4 | 0 | 0 | 1 | 0 | 3.12 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 21 | 0 | 1 | 2 | 3.42 | .290 | 1.23 | 7.4 | 3.9 | 7.4 | 23.2 | 19 | 9 | 9 | 3 | 10 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.35 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 11 | 0 | 2 | 3 | 3.97 | .317 | 1.37 | 9.8 | 2.6 | 4.4 | 45.1 | 49 | 20 | 20 | 5 | 13 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.40 |