| SP | Martinez, P.Martinez, Pedro $ >> | 29 | 2000 | R | 100 | 32 | 32 | 15 | 11 | 3.52 | .280 | 1.16 | 7.8 | 2.6 | 8.8 | 238.0 | 207 | 101 | 93 | 33 | 68 | 234 | 9 | 0 | 0 | 0 | 19 | 3 | 4 | 3.73 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 80 | 30 | 30 | 8 | 17 | 5.33 | .329 | 1.43 | 9.9 | 2.9 | 8.9 | 182.1 | 201 | 113 | 108 | 34 | 59 | 179 | 0 | 0 | 0 | 0 | 13 | 8 | 7 | 4.57 |
| SP | Cicotte, E.Cicotte, Eddie † >> | 33 | 1917 | R | 75 | 30 | 30 | 12 | 9 | 4.46 | .317 | 1.38 | 9.2 | 3.2 | 5.1 | 212.0 | 217 | 110 | 105 | 20 | 76 | 119 | 5 | 0 | 0 | 3 | 13 | 2 | 1 | 4.21 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 29 | 29 | 10 | 12 | 5.15 | .326 | 1.41 | 9.4 | 3.3 | 5.8 | 190.1 | 199 | 122 | 109 | 23 | 70 | 122 | 2 | 0 | 0 | 0 | 13 | 7 | 5 | 4.51 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 61 | 0 | 0 | 6 | 5.75 | .346 | 1.56 | 10.7 | 3.4 | 9.1 | 67.1 | 80 | 50 | 43 | 11 | 25 | 68 | 0 | 4 | 7 | 0 | 0 | 2 | 3 | 4.31 |
| CL | Kimbrel, C.Kimbrel, Craig † $ >> | 24 | 2012 | R | 100 | 56 | 0 | 3 | 6 | 2.20 | .281 | 1.13 | 5.9 | 4.3 | 10.2 | 61.1 | 40 | 17 | 15 | 5 | 29 | 69 | 0 | 29 | 3 | 0 | 0 | 3 | 4 | 3.38 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 69 | 0 | 5 | 2 | 4.57 | .339 | 1.54 | 7.4 | 6.4 | 6.8 | 69.0 | 57 | 41 | 35 | 10 | 49 | 52 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.51 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 48 | 0 | 3 | 2 | 3.61 | .315 | 1.34 | 8.4 | 3.8 | 9.2 | 57.1 | 53 | 27 | 23 | 5 | 24 | 58 | 0 | 1 | 2 | 0 | 0 | 2 | 4 | 3.47 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 43 | 0 | 3 | 0 | 5.19 | .316 | 1.36 | 9.0 | 3.3 | 8.8 | 43.1 | 43 | 25 | 25 | 6 | 16 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.05 |