| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 96 | 34 | 34 | 10 | 15 | 4.06 | .303 | 1.28 | 8.0 | 3.6 | 9.2 | 217.1 | 193 | 101 | 98 | 19 | 86 | 222 | 0 | 0 | 0 | 0 | 18 | 4 | 2 | 3.34 |
| SP | Davis, D.Davis, Doug # >> | 29 | 2004 | L | 66 | 33 | 32 | 16 | 10 | 4.36 | .298 | 1.25 | 8.2 | 3.0 | 6.7 | 198.1 | 180 | 99 | 96 | 24 | 67 | 147 | 0 | 0 | 0 | 0 | 16 | 5 | 1 | 4.18 |
| SP | Lowry, N.Lowry, Noah # >> | 24 | 2004 | L | 59 | 32 | 32 | 7 | 15 | 6.54 | .365 | 1.70 | 11.8 | 3.5 | 5.3 | 152.2 | 200 | 115 | 111 | 24 | 59 | 90 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 5.11 |
| SP | Weaver, J.Weaver, Jeff >> | 28 | 2004 | R | 51 | 32 | 31 | 7 | 17 | 7.59 | .383 | 1.83 | 12.7 | 3.9 | 6.2 | 170.2 | 240 | 154 | 144 | 30 | 73 | 118 | 0 | 0 | 0 | 0 | 7 | 5 | 10 | 5.28 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 86 | 93 | 0 | 7 | 3 | 3.76 | .293 | 1.22 | 7.7 | 3.4 | 6.2 | 131.2 | 112 | 62 | 55 | 16 | 49 | 90 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 4.40 |
| RP | Hoffman, T.Hoffman, Trevor >> | 37 | 2004 | R | 89 | 88 | 0 | 4 | 2 | 4.25 | .329 | 1.41 | 10.6 | 2.1 | 6.8 | 108.0 | 127 | 59 | 51 | 13 | 25 | 81 | 0 | 2 | 1 | 0 | 0 | 7 | 2 | 3.95 |
| RP | Dotel, O.Dotel, Octavio >> | 31 | 2004 | R | 76 | 70 | 0 | 4 | 4 | 4.81 | .326 | 1.41 | 8.7 | 4.2 | 9.7 | 78.2 | 75 | 42 | 42 | 11 | 36 | 84 | 0 | 4 | 4 | 0 | 0 | 3 | 7 | 4.18 |
| RP | Marte, D.Marte, Damaso >> | 29 | 2004 | L | 68 | 57 | 0 | 1 | 2 | 4.64 | .333 | 1.45 | 9.3 | 3.8 | 8.7 | 64.0 | 66 | 34 | 33 | 7 | 27 | 62 | 0 | 3 | 1 | 0 | 0 | 3 | 6 | 3.89 |
| RP | Romero, J.Romero, J.C. >> | 28 | 2004 | L | 50 | 50 | 0 | 3 | 0 | 3.34 | .276 | 1.13 | 6.4 | 3.8 | 6.8 | 62.0 | 44 | 23 | 23 | 10 | 26 | 47 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.89 |