| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 99 | 7 | 7 | 4 | 1 | 4.02 | .305 | 1.30 | 8.8 | 2.9 | 7.7 | 47.0 | 46 | 22 | 21 | 6 | 15 | 40 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 3.98 |
| SP | Garcia, F.Garcia, Freddy >> | 29 | 2004 | R | 85 | 7 | 7 | 2 | 0 | 4.38 | .324 | 1.42 | 9.7 | 3.1 | 7.5 | 49.1 | 53 | 25 | 24 | 1 | 17 | 41 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 2.69 |
| SP | Westbrook, J.Westbrook, Jake >> | 27 | 2004 | R | 64 | 7 | 6 | 2 | 3 | 4.17 | .353 | 1.64 | 11.3 | 3.8 | 6.5 | 36.2 | 45 | 20 | 17 | 3 | 15 | 26 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 3.89 |
| SP | Vazquez, J.Vazquez, Javier # >> | 28 | 2004 | R | 62 | 6 | 6 | 1 | 3 | 5.70 | .323 | 1.43 | 10.5 | 2.5 | 6.8 | 36.1 | 42 | 24 | 23 | 5 | 10 | 27 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 4.14 |
| SP | Williams, W.Williams, Woody >> | 38 | 2004 | R | 44 | 6 | 6 | 0 | 4 | 9.10 | .381 | 1.85 | 13.8 | 3.2 | 4.8 | 28.2 | 43 | 29 | 29 | 7 | 10 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.25 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 86 | 20 | 0 | 0 | 1 | 2.57 | .282 | 1.18 | 7.1 | 3.5 | 5.8 | 28.0 | 22 | 8 | 8 | 1 | 11 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.36 |
| RP | Hoffman, T.Hoffman, Trevor >> | 37 | 2004 | R | 89 | 14 | 0 | 3 | 0 | 7.24 | .397 | 1.98 | 12.5 | 6.2 | 5.5 | 13.2 | 18 | 12 | 11 | 2 | 9 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.85 |
| RP | Dotel, O.Dotel, Octavio >> | 31 | 2004 | R | 76 | 10 | 0 | 1 | 2 | 7.71 | .453 | 2.49 | 13.9 | 9.8 | 10.6 | 11.2 | 17 | 11 | 10 | 1 | 12 | 13 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 5.09 |
| RP | Shouse, B.Shouse, Brian >> | 36 | 2004 | L | 64 | 12 | 0 | 1 | 0 | 1.64 | .214 | 0.82 | 4.1 | 3.3 | 6.5 | 11.0 | 5 | 2 | 2 | 1 | 4 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.82 |
| RP | Duchscherer, J.Duchscherer, Justin >> | 27 | 2004 | R | 55 | 9 | 0 | 1 | 1 | 0.71 | .208 | 0.79 | 6.8 | 0.8 | 6.8 | 12.2 | 9 | 1 | 1 | 0 | 1 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.75 |
| CL | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 96 | 15 | 0 | 1 | 1 | 4.08 | .254 | 1.02 | 5.3 | 4.2 | 9.5 | 17.2 | 10 | 8 | 8 | 1 | 8 | 18 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 3.06 |