| SP | Carpenter, C.Carpenter, Chris >> | 29 | 2004 | R | 90 | 19 | 19 | 7 | 8 | 4.55 | .328 | 1.46 | 9.9 | 3.3 | 6.0 | 112.2 | 123 | 57 | 57 | 19 | 41 | 75 | 0 | 0 | 0 | 0 | 12 | 1 | 0 | 4.99 |
| SP | Beckett, J.Beckett, Josh † >> | 24 | 2004 | R | 87 | 18 | 18 | 8 | 7 | 4.01 | .304 | 1.26 | 9.1 | 2.3 | 7.3 | 112.1 | 113 | 52 | 50 | 13 | 28 | 91 | 0 | 0 | 0 | 0 | 12 | 6 | 5 | 3.79 |
| SP | Westbrook, J.Westbrook, Jake >> | 27 | 2004 | R | 64 | 18 | 18 | 9 | 6 | 4.83 | .321 | 1.38 | 9.5 | 3.0 | 5.4 | 113.2 | 119 | 62 | 61 | 17 | 38 | 68 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 4.87 |
| SP | Buehrle, M.Buehrle, Mark # >> | 25 | 2004 | L | 52 | 18 | 18 | 8 | 5 | 5.38 | .335 | 1.46 | 11.3 | 1.9 | 5.5 | 112.0 | 140 | 72 | 67 | 23 | 24 | 68 | 2 | 0 | 0 | 0 | 8 | 5 | 0 | 5.23 |
| SP | Milton, E.Milton, Eric >> | 29 | 2004 | L | 46 | 18 | 18 | 3 | 8 | 5.86 | .352 | 1.59 | 10.7 | 3.7 | 6.9 | 101.1 | 120 | 68 | 66 | 19 | 41 | 77 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 5.26 |
| RP | Madson, R.Madson, Ryan >> | 24 | 2004 | R | 70 | 43 | 0 | 4 | 2 | 6.09 | .328 | 1.42 | 8.8 | 4.1 | 6.1 | 44.1 | 43 | 32 | 30 | 8 | 20 | 30 | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 5.50 |
| RP | Worrell, T.Worrell, Tim >> | 37 | 2004 | R | 51 | 22 | 0 | 1 | 0 | 4.79 | .303 | 1.26 | 9.5 | 2.3 | 6.3 | 20.2 | 21 | 12 | 11 | 5 | 5 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.75 |
| SU | Hoffman, T.Hoffman, Trevor >> | 37 | 2004 | R | 89 | 32 | 0 | 2 | 2 | 3.15 | .237 | 0.93 | 7.4 | 1.1 | 5.8 | 34.1 | 28 | 12 | 12 | 5 | 4 | 22 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.97 |
| CL | Gonzalez, M.Gonzalez, Mike † >> | 26 | 2004 | L | 92 | 35 | 0 | 0 | 4 | 3.79 | .262 | 1.01 | 7.7 | 1.5 | 9.8 | 35.2 | 30 | 16 | 15 | 4 | 6 | 38 | 0 | 24 | 0 | 0 | 0 | 2 | 1 | 3.00 |