| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 100 | 19 | 19 | 6 | 9 | 4.50 | .318 | 1.35 | 10.1 | 2.0 | 9.4 | 118.0 | 133 | 61 | 59 | 15 | 26 | 123 | 3 | 0 | 0 | 1 | 10 | 6 | 2 | 3.38 |
| SP | Garcia, F.Garcia, Freddy >> | 29 | 2004 | R | 85 | 19 | 19 | 6 | 3 | 4.28 | .332 | 1.43 | 9.9 | 3.0 | 6.8 | 120.0 | 132 | 61 | 57 | 14 | 40 | 90 | 2 | 0 | 0 | 0 | 12 | 7 | 1 | 4.19 |
| SP | Bonderman, J.Bonderman, Jeremy >> | 22 | 2004 | R | 70 | 18 | 18 | 10 | 5 | 4.91 | .355 | 1.59 | 10.5 | 3.8 | 6.0 | 88.0 | 103 | 52 | 48 | 11 | 37 | 59 | 0 | 0 | 0 | 0 | 5 | 5 | 2 | 4.72 |
| SP | Vazquez, J.Vazquez, Javier # >> | 28 | 2004 | R | 62 | 19 | 18 | 8 | 8 | 5.66 | .331 | 1.45 | 9.9 | 3.2 | 6.1 | 97.0 | 107 | 61 | 61 | 11 | 34 | 66 | 0 | 0 | 0 | 0 | 8 | 3 | 5 | 4.26 |
| SP | Morris, M.Morris, Matt >> | 30 | 2004 | R | 48 | 18 | 17 | 9 | 4 | 4.42 | .331 | 1.46 | 9.6 | 3.6 | 5.0 | 97.2 | 104 | 54 | 48 | 8 | 39 | 54 | 0 | 0 | 0 | 0 | 9 | 2 | 3 | 4.23 |
| CL | Benitez, A.Benitez, Armando † >> | 32 | 2004 | R | 96 | 34 | 0 | 2 | 1 | 1.90 | .229 | 0.89 | 5.4 | 2.8 | 8.1 | 42.2 | 25 | 9 | 9 | 2 | 13 | 38 | 0 | 16 | 3 | 0 | 0 | 0 | 0 | 2.74 |
| RP | Foulke, K.Foulke, Keith >> | 32 | 2004 | R | 87 | 49 | 0 | 2 | 3 | 4.38 | .309 | 1.32 | 9.4 | 2.6 | 7.4 | 51.1 | 53 | 25 | 25 | 3 | 15 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.06 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 86 | 46 | 0 | 3 | 0 | 4.56 | .328 | 1.40 | 10.2 | 2.5 | 5.6 | 51.1 | 58 | 26 | 26 | 9 | 14 | 32 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 5.04 |
| RP | Dotel, O.Dotel, Octavio >> | 31 | 2004 | R | 76 | 27 | 0 | 1 | 1 | 3.73 | .254 | 1.02 | 5.5 | 3.8 | 9.6 | 31.1 | 19 | 13 | 13 | 6 | 13 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.65 |
| RP | Alvarez, W.Alvarez, Wilson >> | 34 | 2004 | L | 66 | 47 | 0 | 2 | 2 | 4.71 | .276 | 1.08 | 6.9 | 2.9 | 6.7 | 63.0 | 48 | 33 | 33 | 7 | 20 | 47 | 0 | 1 | 4 | 0 | 0 | 4 | 1 | 4.10 |
| RP | Bottalico, R.Bottalico, Ricky >> | 35 | 2004 | R | 57 | 27 | 0 | 1 | 2 | 3.66 | .304 | 1.31 | 6.8 | 5.1 | 6.5 | 32.0 | 24 | 15 | 13 | 2 | 18 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 5 | 4.06 |
| RP | Dohmann, S.Dohmann, Scott >> | 26 | 2004 | R | 49 | 24 | 0 | 2 | 1 | 3.21 | .333 | 1.46 | 7.7 | 5.5 | 9.0 | 28.0 | 24 | 11 | 10 | 4 | 17 | 28 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.79 |
| RP | Harikkala, T.Harikkala, Tim >> | 33 | 2004 | R | 43 | 11 | 0 | 0 | 0 | 3.75 | .333 | 1.50 | 9.8 | 3.8 | 4.5 | 12.0 | 13 | 5 | 5 | 3 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.50 |