| SP | Zambrano, C.Zambrano, Carlos >> | 23 | 2004 | R | 91 | 12 | 12 | 4 | 3 | 4.11 | .328 | 1.47 | 10.4 | 2.9 | 5.9 | 72.1 | 83 | 37 | 33 | 9 | 23 | 47 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.28 |
| SP | Beckett, J.Beckett, Josh >> | 24 | 2004 | R | 87 | 12 | 12 | 3 | 5 | 6.79 | .357 | 1.65 | 10.7 | 4.3 | 6.6 | 63.2 | 75 | 49 | 48 | 10 | 30 | 46 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.08 |
| SP | Perez, O.Perez, Odalis >> | 27 | 2004 | L | 86 | 12 | 12 | 4 | 3 | 4.50 | .325 | 1.44 | 9.7 | 3.3 | 5.6 | 68.0 | 73 | 34 | 34 | 4 | 25 | 42 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 3.63 |
| SP | Lopez, R.Lopez, Rodrigo >> | 29 | 2004 | R | 65 | 12 | 12 | 2 | 2 | 2.60 | .291 | 1.17 | 7.4 | 3.3 | 6.2 | 55.1 | 45 | 20 | 16 | 4 | 20 | 38 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 3.82 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 96 | 31 | 0 | 8 | 1 | 2.82 | .239 | 0.88 | 4.9 | 3.0 | 5.1 | 51.0 | 28 | 18 | 16 | 8 | 17 | 29 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 5.08 |
| RP | Aquino, G.Aquino, Greg >> | 26 | 2004 | R | 80 | 28 | 0 | 1 | 0 | 5.26 | .354 | 1.59 | 8.3 | 6.3 | 5.1 | 37.2 | 34 | 24 | 22 | 8 | 26 | 21 | 0 | 2 | 1 | 0 | 0 | 2 | 2 | 6.95 |
| RP | Mota, G.Mota, Guillermo >> | 31 | 2004 | R | 78 | 27 | 0 | 2 | 1 | 5.13 | .342 | 1.50 | 10.1 | 3.5 | 6.8 | 33.1 | 37 | 20 | 19 | 2 | 13 | 25 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 3.64 |
| RP | Miller, M.Miller, Matt >> | 33 | 2004 | R | 77 | 30 | 0 | 1 | 2 | 2.61 | .278 | 1.13 | 7.3 | 2.8 | 8.3 | 38.0 | 31 | 11 | 11 | 3 | 12 | 35 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 3.21 |
| RP | Madson, R.Madson, Ryan >> | 24 | 2004 | R | 70 | 22 | 0 | 4 | 3 | 5.79 | .327 | 1.41 | 9.4 | 3.5 | 6.7 | 23.1 | 24 | 15 | 15 | 5 | 9 | 17 | 0 | 3 | 4 | 0 | 0 | 1 | 1 | 5.65 |
| RP | Marte, D.Marte, Damaso >> | 29 | 2004 | L | 68 | 21 | 0 | 0 | 2 | 3.33 | .324 | 1.44 | 7.1 | 6.0 | 7.1 | 24.1 | 19 | 10 | 9 | 4 | 16 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 5.58 |
| SP | Morris, M.Morris, Matt >> | 30 | 2004 | R | 48 | 8 | 0 | 1 | 2 | 5.28 | .313 | 1.37 | 10.2 | 2.4 | 7.8 | 15.1 | 17 | 10 | 9 | 2 | 4 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.80 |