| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 24 | 23 | 7 | 9 | 4.30 | .299 | 1.28 | 8.2 | 3.3 | 8.8 | 155.0 | 142 | 79 | 74 | 23 | 56 | 151 | 1 | 0 | 0 | 1 | 13 | 0 | 2 | 4.06 |
| SP | Gallen, Z.Gallen, Zac † >> | 26 | 2022 | R | 93 | 26 | 26 | 14 | 6 | 2.80 | .261 | 1.04 | 6.6 | 2.7 | 9.8 | 167.1 | 123 | 58 | 52 | 20 | 51 | 182 | 2 | 0 | 0 | 1 | 18 | 3 | 1 | 3.35 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 90 | 26 | 26 | 8 | 9 | 4.44 | .292 | 1.22 | 8.9 | 2.0 | 10.2 | 178.1 | 177 | 91 | 88 | 34 | 40 | 201 | 3 | 0 | 0 | 1 | 14 | 4 | 0 | 3.97 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 74 | 25 | 23 | 10 | 8 | 4.53 | .314 | 1.35 | 8.5 | 3.6 | 6.7 | 171.0 | 162 | 91 | 86 | 30 | 69 | 128 | 7 | 0 | 0 | 2 | 10 | 4 | 5 | 5.06 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 26 | 26 | 8 | 3 | 4.18 | .310 | 1.32 | 7.2 | 4.7 | 9.8 | 131.1 | 105 | 68 | 61 | 13 | 69 | 143 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 3.76 |
| RP | Edwards, C.Edwards, Carl # >> | 24 | 2016 | R | 93 | 61 | 0 | 6 | 3 | 5.11 | .364 | 1.69 | 8.6 | 6.8 | 10.2 | 68.2 | 65 | 40 | 39 | 6 | 51 | 77 | 0 | 5 | 7 | 0 | 0 | 2 | 3 | 4.22 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 41 | 0 | 3 | 0 | 4.60 | .325 | 1.40 | 6.1 | 6.5 | 10.5 | 47.0 | 32 | 26 | 24 | 6 | 34 | 55 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 4.62 |
| RP | Harvey, B.Harvey, Bryan # >> | 28 | 1991 | R | 64 | 41 | 0 | 6 | 2 | 5.02 | .339 | 1.49 | 8.5 | 5.1 | 9.2 | 37.2 | 35 | 22 | 21 | 5 | 21 | 38 | 0 | 7 | 2 | 0 | 0 | 2 | 2 | 4.57 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 31 | 0 | 4 | 2 | 3.86 | .319 | 1.38 | 7.3 | 5.3 | 8.7 | 32.2 | 26 | 18 | 14 | 9 | 19 | 31 | 0 | 4 | 2 | 0 | 0 | 1 | 2 | 6.59 |