| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 29 | 29 | 10 | 13 | 5.30 | .344 | 1.54 | 11.0 | 2.9 | 8.1 | 200.1 | 244 | 129 | 118 | 36 | 65 | 179 | 4 | 0 | 0 | 1 | 11 | 6 | 7 | 4.62 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 29 | 29 | 11 | 14 | 4.68 | .303 | 1.27 | 8.3 | 3.2 | 6.8 | 204.0 | 188 | 112 | 106 | 29 | 72 | 154 | 4 | 0 | 0 | 1 | 12 | 6 | 0 | 4.49 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 64 | 28 | 28 | 7 | 18 | 5.25 | .327 | 1.46 | 10.6 | 2.5 | 6.8 | 200.2 | 236 | 125 | 117 | 44 | 56 | 151 | 4 | 0 | 0 | 1 | 9 | 1 | 2 | 5.21 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 28 | 28 | 8 | 16 | 5.31 | .326 | 1.45 | 10.4 | 2.7 | 7.1 | 193.1 | 224 | 117 | 114 | 31 | 57 | 153 | 2 | 0 | 0 | 2 | 11 | 0 | 3 | 4.39 |
| SP | DeLeon, J.DeLeon, Jose >> | 29 | 1989 | R | 59 | 27 | 27 | 8 | 15 | 4.76 | .324 | 1.39 | 8.5 | 4.0 | 6.5 | 181.2 | 171 | 102 | 96 | 29 | 81 | 131 | 2 | 0 | 0 | 0 | 12 | 9 | 3 | 5.13 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 57 | 0 | 1 | 6 | 4.75 | .292 | 1.24 | 9.5 | 1.8 | 9.8 | 60.2 | 63 | 33 | 32 | 13 | 12 | 65 | 0 | 6 | 1 | 0 | 0 | 0 | 2 | 4.25 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 37 | 0 | 2 | 3 | 2.64 | .269 | 1.08 | 6.5 | 3.3 | 9.2 | 44.1 | 32 | 14 | 13 | 1 | 16 | 45 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 2.41 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 23 | 0 | 1 | 0 | 3.32 | .316 | 1.38 | 6.0 | 6.9 | 13.3 | 21.2 | 14 | 8 | 8 | 2 | 16 | 31 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.57 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 20 | 0 | 0 | 0 | 6.17 | .346 | 1.59 | 9.4 | 5.1 | 12.5 | 23.1 | 24 | 16 | 16 | 3 | 13 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.61 |