| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 17 | 17 | 8 | 6 | 3.88 | .284 | 1.16 | 7.7 | 2.8 | 9.9 | 125.1 | 107 | 56 | 54 | 14 | 39 | 137 | 1 | 0 | 0 | 0 | 9 | 3 | 2 | 3.27 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 16 | 16 | 6 | 6 | 3.89 | .294 | 1.23 | 8.0 | 3.1 | 9.1 | 122.2 | 109 | 59 | 53 | 17 | 42 | 123 | 2 | 0 | 0 | 0 | 7 | 2 | 3 | 3.88 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 16 | 16 | 9 | 6 | 4.38 | .342 | 1.54 | 8.5 | 5.4 | 9.7 | 109.0 | 103 | 54 | 53 | 11 | 65 | 118 | 0 | 0 | 0 | 0 | 9 | 2 | 3 | 3.99 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 16 | 16 | 8 | 5 | 6.34 | .351 | 1.60 | 10.6 | 3.8 | 5.7 | 99.1 | 117 | 73 | 70 | 22 | 42 | 63 | 0 | 0 | 0 | 0 | 5 | 2 | 3 | 5.95 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 49 | 0 | 1 | 3 | 4.71 | .265 | 1.06 | 7.6 | 2.1 | 10.3 | 57.1 | 48 | 30 | 30 | 11 | 13 | 65 | 0 | 6 | 2 | 0 | 0 | 1 | 1 | 3.96 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 35 | 0 | 2 | 3 | 3.58 | .319 | 1.41 | 8.5 | 4.4 | 8.0 | 37.2 | 35 | 16 | 15 | 7 | 18 | 33 | 0 | 7 | 1 | 0 | 0 | 0 | 2 | 5.14 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 13 | 0 | 3 | 0 | 1.32 | .226 | 0.88 | 5.5 | 2.8 | 5.5 | 13.2 | 8 | 3 | 2 | 1 | 4 | 8 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.69 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 12 | 0 | 0 | 0 | 1.29 | .236 | 0.86 | 3.2 | 4.5 | 10.9 | 14.0 | 5 | 2 | 2 | 1 | 7 | 17 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.21 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 54 | 3 | 0 | 0 | 1 | 20.25 | .636 | 5.25 | 54.0 | 9.0 | 18.0 | 1.1 | 6 | 3 | 3 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.00 |