| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 14 | 14 | 7 | 5 | 3.45 | .281 | 1.15 | 7.6 | 2.7 | 9.8 | 99.0 | 84 | 42 | 38 | 9 | 30 | 108 | 3 | 0 | 0 | 1 | 10 | 2 | 3 | 2.97 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 13 | 13 | 5 | 4 | 3.74 | .265 | 1.04 | 7.7 | 1.7 | 10.8 | 91.1 | 78 | 39 | 38 | 18 | 17 | 109 | 4 | 0 | 0 | 2 | 8 | 4 | 2 | 3.87 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 73 | 13 | 13 | 2 | 2 | 6.34 | .322 | 1.39 | 9.8 | 2.8 | 7.1 | 65.1 | 71 | 48 | 46 | 9 | 20 | 51 | 1 | 0 | 0 | 0 | 5 | 2 | 2 | 4.25 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 13 | 13 | 4 | 5 | 6.78 | .348 | 1.58 | 11.9 | 2.5 | 9.4 | 66.1 | 87 | 51 | 50 | 19 | 18 | 69 | 0 | 0 | 0 | 0 | 5 | 1 | 4 | 5.52 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 37 | 0 | 1 | 2 | 4.17 | .289 | 1.22 | 8.8 | 2.2 | 9.9 | 41.0 | 40 | 20 | 19 | 6 | 10 | 45 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 3.44 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 29 | 0 | 3 | 0 | 3.72 | .261 | 1.03 | 6.6 | 2.8 | 6.9 | 38.2 | 28 | 16 | 16 | 6 | 12 | 29 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.55 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 87 | 41 | 0 | 1 | 2 | 3.82 | .272 | 1.06 | 6.8 | 2.7 | 11.2 | 33.0 | 25 | 14 | 14 | 6 | 10 | 41 | 0 | 3 | 2 | 0 | 0 | 2 | 1 | 3.97 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 26 | 0 | 2 | 2 | 6.23 | .316 | 1.38 | 6.9 | 5.5 | 8.0 | 26.0 | 20 | 19 | 18 | 5 | 16 | 23 | 0 | 2 | 5 | 0 | 0 | 0 | 4 | 5.58 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 28 | 0 | 2 | 2 | 4.03 | .293 | 1.24 | 8.7 | 2.5 | 10.9 | 29.0 | 28 | 14 | 13 | 3 | 8 | 35 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 2.76 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 55 | 22 | 0 | 1 | 1 | 5.70 | .330 | 1.48 | 11.7 | 2.0 | 11.0 | 23.2 | 30 | 15 | 15 | 7 | 5 | 28 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 5.17 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 10 | 0 | 3 | 1 | 2.21 | .291 | 1.23 | 9.0 | 2.3 | 5.4 | 20.1 | 20 | 5 | 5 | 2 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.85 |