| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 7 | 7 | 1 | 6 | 6.75 | .333 | 1.50 | 10.7 | 2.9 | 3.9 | 37.1 | 44 | 28 | 28 | 5 | 12 | 16 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 4.86 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 7 | 7 | 0 | 3 | 8.37 | .398 | 1.89 | 13.6 | 3.5 | 5.2 | 33.1 | 50 | 32 | 31 | 6 | 13 | 19 | 1 | 0 | 0 | 0 | 1 | 3 | 0 | 5.67 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 5 | 5 | 1 | 2 | 9.70 | .396 | 1.97 | 12.9 | 5.1 | 4.3 | 21.1 | 30 | 23 | 23 | 3 | 12 | 10 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 5.62 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 18 | 0 | 2 | 0 | 3.25 | .278 | 1.12 | 8.0 | 2.3 | 8.7 | 27.2 | 24 | 10 | 10 | 0 | 7 | 26 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 1.96 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 19 | 0 | 2 | 1 | 1.78 | .202 | 0.76 | 3.9 | 3.0 | 9.6 | 30.1 | 13 | 7 | 6 | 2 | 10 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.73 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 15 | 0 | 2 | 1 | 5.40 | .310 | 1.30 | 9.9 | 1.8 | 7.7 | 20.0 | 22 | 12 | 12 | 3 | 4 | 17 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.00 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 5 | 2 | 1 | 1 | 7.62 | .361 | 1.69 | 11.1 | 4.2 | 5.5 | 13.0 | 16 | 11 | 11 | 1 | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.15 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 5 | 0 | 0 | 0 | 15.43 | .462 | 2.57 | 27.0 | 0.0 | 6.8 | 4.2 | 12 | 9 | 8 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 10 | 1 | 1 | 1 | 5.55 | .360 | 1.56 | 9.8 | 4.5 | 4.1 | 24.1 | 26 | 15 | 15 | 3 | 12 | 11 | 1 | 4 | 1 | 0 | 1 | 3 | 1 | 5.58 |