| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 33 | 33 | 7 | 17 | 5.26 | .321 | 1.40 | 9.4 | 3.2 | 4.7 | 205.1 | 214 | 132 | 120 | 28 | 73 | 106 | 8 | 0 | 0 | 0 | 13 | 4 | 3 | 4.87 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 32 | 32 | 10 | 13 | 5.27 | .338 | 1.50 | 10.1 | 3.5 | 4.6 | 184.1 | 206 | 109 | 108 | 27 | 71 | 94 | 8 | 0 | 0 | 4 | 11 | 5 | 5 | 5.13 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 29 | 29 | 5 | 9 | 6.35 | .357 | 1.66 | 10.4 | 4.5 | 4.9 | 139.0 | 161 | 104 | 98 | 19 | 70 | 75 | 0 | 0 | 0 | 0 | 12 | 1 | 5 | 5.23 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 81 | 0 | 8 | 1 | 3.69 | .306 | 1.28 | 7.9 | 3.6 | 8.4 | 117.0 | 103 | 51 | 48 | 14 | 47 | 109 | 0 | 5 | 0 | 0 | 0 | 5 | 2 | 4.03 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 81 | 0 | 6 | 5 | 3.80 | .291 | 1.19 | 7.5 | 3.2 | 9.6 | 109.0 | 91 | 49 | 46 | 12 | 39 | 116 | 0 | 6 | 6 | 0 | 0 | 4 | 5 | 3.49 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 65 | 0 | 4 | 6 | 4.19 | .294 | 1.22 | 8.4 | 2.7 | 8.1 | 81.2 | 76 | 40 | 38 | 12 | 24 | 73 | 0 | 6 | 2 | 0 | 0 | 2 | 2 | 4.09 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 6 | 2 | 1 | 2 | 7.90 | .369 | 1.76 | 12.5 | 4.2 | 6.2 | 13.2 | 18 | 12 | 12 | 1 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 14 | 0 | 0 | 1 | 6.11 | .338 | 1.53 | 10.6 | 3.7 | 6.4 | 17.2 | 20 | 13 | 12 | 2 | 7 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.35 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 46 | 1 | 8 | 10 | 5.19 | .362 | 1.64 | 10.4 | 4.5 | 4.7 | 112.2 | 129 | 68 | 65 | 9 | 56 | 59 | 1 | 5 | 5 | 0 | 1 | 7 | 2 | 4.68 |