| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 18 | 18 | 8 | 4 | 3.66 | .280 | 1.13 | 7.8 | 2.4 | 9.7 | 118.0 | 102 | 48 | 48 | 14 | 31 | 127 | 1 | 0 | 0 | 1 | 13 | 5 | 0 | 3.31 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 16 | 16 | 1 | 7 | 4.59 | .322 | 1.39 | 8.3 | 4.2 | 3.4 | 96.0 | 88 | 53 | 49 | 10 | 45 | 36 | 0 | 0 | 0 | 0 | 8 | 4 | 3 | 5.14 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 40 | 0 | 4 | 1 | 2.64 | .249 | 0.98 | 7.2 | 1.6 | 9.7 | 61.1 | 49 | 22 | 18 | 6 | 11 | 66 | 0 | 2 | 4 | 0 | 0 | 1 | 3 | 2.70 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 42 | 0 | 2 | 2 | 3.88 | .323 | 1.39 | 8.6 | 3.9 | 7.8 | 51.0 | 49 | 29 | 22 | 6 | 22 | 44 | 0 | 3 | 3 | 0 | 0 | 2 | 2 | 4.22 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 26 | 0 | 3 | 2 | 2.25 | .288 | 1.21 | 8.0 | 2.9 | 9.3 | 28.0 | 25 | 7 | 7 | 1 | 9 | 29 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 2.36 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 19 | 0 | 2 | 0 | 6.04 | .337 | 1.48 | 9.8 | 3.7 | 6.5 | 22.1 | 24 | 15 | 15 | 5 | 9 | 16 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 5.86 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 5 | 1 | 0 | 0 | 2.00 | .229 | 0.89 | 6.0 | 2.0 | 7.0 | 9.0 | 6 | 2 | 2 | 2 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |