| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 18 | 18 | 8 | 9 | 4.35 | .274 | 1.10 | 8.1 | 1.8 | 8.7 | 132.1 | 119 | 69 | 64 | 22 | 26 | 128 | 4 | 0 | 0 | 0 | 10 | 5 | 4 | 3.93 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 17 | 17 | 4 | 9 | 5.28 | .311 | 1.33 | 9.0 | 3.1 | 7.8 | 117.2 | 117 | 74 | 69 | 20 | 40 | 101 | 1 | 0 | 0 | 0 | 9 | 2 | 1 | 4.57 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 46 | 0 | 2 | 3 | 3.79 | .305 | 1.31 | 8.7 | 3.2 | 11.1 | 61.2 | 59 | 27 | 26 | 4 | 22 | 75 | 0 | 1 | 2 | 0 | 0 | 0 | 5 | 2.48 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 38 | 0 | 4 | 2 | 3.02 | .306 | 1.32 | 6.3 | 5.7 | 9.4 | 44.2 | 31 | 19 | 15 | 4 | 28 | 46 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 25 | 0 | 2 | 1 | 3.98 | .326 | 1.42 | 7.5 | 5.5 | 8.4 | 31.2 | 26 | 14 | 14 | 4 | 19 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.74 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 10 | 0 | 1 | 1 | 1.80 | .302 | 1.30 | 6.3 | 5.4 | 4.5 | 10.0 | 7 | 2 | 2 | 1 | 6 | 5 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.10 |