| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 28 | 28 | 7 | 11 | 4.73 | .325 | 1.42 | 8.4 | 4.4 | 8.7 | 180.2 | 168 | 107 | 95 | 24 | 88 | 173 | 1 | 0 | 0 | 0 | 12 | 5 | 0 | 4.36 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 29 | 29 | 10 | 14 | 4.72 | .278 | 1.15 | 8.5 | 1.8 | 7.9 | 192.2 | 182 | 104 | 101 | 38 | 39 | 168 | 7 | 0 | 0 | 1 | 13 | 2 | 2 | 4.46 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 30 | 30 | 4 | 18 | 6.01 | .355 | 1.63 | 10.9 | 3.8 | 7.9 | 181.1 | 220 | 122 | 121 | 19 | 76 | 158 | 1 | 0 | 0 | 0 | 9 | 3 | 2 | 3.93 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 25 | 25 | 7 | 11 | 4.80 | .352 | 1.59 | 9.5 | 4.9 | 4.8 | 140.2 | 148 | 83 | 75 | 15 | 76 | 74 | 0 | 0 | 0 | 0 | 9 | 5 | 2 | 5.07 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 80 | 0 | 3 | 5 | 3.56 | .284 | 1.14 | 7.4 | 2.9 | 8.3 | 108.2 | 89 | 47 | 43 | 9 | 35 | 100 | 0 | 4 | 9 | 0 | 0 | 5 | 0 | 3.34 |
| RP | Dotel, O.Dotel, Octavio # >> | 29 | 2002 | R | 69 | 74 | 0 | 5 | 6 | 4.79 | .317 | 1.38 | 8.8 | 3.6 | 8.6 | 92.0 | 90 | 50 | 49 | 13 | 37 | 88 | 0 | 6 | 4 | 0 | 0 | 1 | 5 | 4.16 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 56 | 0 | 1 | 6 | 4.57 | .326 | 1.43 | 9.4 | 3.5 | 6.9 | 67.0 | 70 | 39 | 34 | 15 | 26 | 51 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 5.60 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 44 | 0 | 2 | 2 | 4.24 | .295 | 1.24 | 8.6 | 2.5 | 6.5 | 51.0 | 49 | 31 | 24 | 11 | 14 | 37 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.24 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 6 | 2 | 0 | 2 | 8.84 | .383 | 1.86 | 14.2 | 2.8 | 5.2 | 19.1 | 30 | 25 | 19 | 7 | 6 | 11 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 7.58 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 17 | 1 | 0 | 3 | 9.25 | .392 | 1.93 | 13.1 | 4.5 | 6.8 | 24.1 | 35 | 27 | 25 | 13 | 12 | 18 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 10.04 |