| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 32 | 32 | 7 | 9 | 4.36 | .293 | 1.23 | 8.8 | 2.3 | 9.7 | 198.1 | 193 | 96 | 96 | 21 | 51 | 214 | 0 | 0 | 0 | 0 | 17 | 2 | 0 | 3.02 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 31 | 31 | 11 | 11 | 5.04 | .315 | 1.38 | 9.7 | 2.8 | 8.3 | 207.1 | 222 | 125 | 116 | 28 | 64 | 190 | 4 | 0 | 0 | 1 | 12 | 0 | 7 | 3.85 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 31 | 31 | 16 | 8 | 4.27 | .307 | 1.31 | 9.1 | 2.7 | 4.9 | 223.2 | 226 | 107 | 106 | 17 | 66 | 122 | 7 | 0 | 0 | 2 | 18 | 5 | 5 | 3.85 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 29 | 29 | 8 | 15 | 6.12 | .346 | 1.58 | 9.6 | 4.7 | 6.8 | 163.1 | 173 | 115 | 111 | 29 | 85 | 123 | 0 | 0 | 0 | 0 | 11 | 1 | 0 | 5.39 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 34 | 0 | 1 | 3 | 6.39 | .396 | 1.94 | 10.5 | 7.0 | 9.0 | 31.0 | 36 | 22 | 22 | 5 | 24 | 31 | 0 | 3 | 2 | 0 | 0 | 1 | 3 | 5.52 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 16 | 0 | 1 | 2 | 7.11 | .356 | 1.58 | 8.3 | 6.8 | 10.5 | 12.2 | 11 | 10 | 10 | 0 | 9 | 14 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.17 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 17 | 0 | 1 | 1 | 8.84 | .402 | 2.02 | 12.5 | 6.0 | 7.0 | 18.1 | 25 | 18 | 18 | 6 | 12 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 7.78 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 27 | 0 | 1 | 0 | 2.90 | .295 | 1.23 | 8.7 | 2.3 | 7.8 | 31.0 | 30 | 10 | 10 | 5 | 8 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.23 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 21 | 0 | 3 | 3 | 6.72 | .372 | 1.73 | 10.4 | 5.2 | 6.1 | 88.1 | 102 | 66 | 66 | 19 | 51 | 60 | 0 | 0 | 0 | 0 | 0 | 4 | 6 | 6.32 |