| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 28 | 28 | 8 | 5 | 3.72 | .293 | 1.22 | 9.1 | 1.9 | 8.3 | 193.1 | 195 | 82 | 80 | 18 | 41 | 178 | 2 | 0 | 0 | 0 | 19 | 4 | 3 | 3.07 |
| SP | Richard, J.Richard, J.R. # >> | 30 | 1980 | R | 90 | 27 | 27 | 4 | 16 | 5.50 | .330 | 1.45 | 9.0 | 4.0 | 7.7 | 147.1 | 147 | 93 | 90 | 20 | 66 | 126 | 2 | 0 | 0 | 1 | 10 | 5 | 5 | 4.50 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 27 | 27 | 11 | 10 | 3.86 | .284 | 1.17 | 8.3 | 2.3 | 4.7 | 191.0 | 176 | 86 | 82 | 17 | 48 | 99 | 7 | 0 | 0 | 2 | 16 | 3 | 2 | 3.92 |
| SP | Reulbach, E.Reulbach, Ed # >> | 24 | 1906 | R | 60 | 27 | 27 | 10 | 7 | 4.10 | .309 | 1.32 | 7.9 | 3.9 | 4.5 | 167.0 | 147 | 78 | 76 | 14 | 73 | 83 | 3 | 0 | 0 | 1 | 14 | 4 | 4 | 4.48 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 25 | 25 | 12 | 7 | 4.16 | .320 | 1.39 | 7.9 | 4.7 | 4.5 | 162.1 | 142 | 80 | 75 | 13 | 84 | 81 | 2 | 0 | 0 | 1 | 14 | 3 | 1 | 4.65 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 59 | 0 | 6 | 9 | 3.84 | .304 | 1.28 | 7.5 | 4.2 | 8.0 | 65.2 | 54 | 31 | 28 | 7 | 30 | 58 | 0 | 25 | 7 | 0 | 0 | 2 | 1 | 4.09 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 71 | 0 | 8 | 2 | 4.04 | .283 | 1.14 | 7.5 | 2.8 | 8.1 | 91.1 | 76 | 46 | 41 | 9 | 28 | 82 | 0 | 2 | 2 | 0 | 0 | 4 | 0 | 3.54 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 60 | 0 | 3 | 2 | 4.60 | .331 | 1.47 | 9.6 | 3.7 | 8.2 | 58.2 | 62 | 31 | 30 | 9 | 24 | 53 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 4.48 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 40 | 0 | 7 | 2 | 1.86 | .286 | 1.20 | 6.5 | 4.4 | 7.8 | 53.1 | 38 | 13 | 11 | 6 | 26 | 46 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.21 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 38 | 0 | 1 | 2 | 2.76 | .249 | 0.99 | 5.8 | 3.2 | 9.6 | 42.1 | 27 | 14 | 13 | 4 | 15 | 45 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 3.17 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 29 | 0 | 0 | 0 | 2.08 | .288 | 1.15 | 5.3 | 5.3 | 10.9 | 34.2 | 20 | 9 | 8 | 2 | 20 | 41 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.29 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 7 | 1 | 2 | 1 | 3.94 | .252 | 0.98 | 7.8 | 1.2 | 9.9 | 29.2 | 25 | 13 | 13 | 6 | 4 | 32 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.00 |