| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 30 | 30 | 13 | 9 | 2.93 | .294 | 1.23 | 7.5 | 3.6 | 7.0 | 184.1 | 153 | 66 | 60 | 15 | 74 | 144 | 1 | 0 | 0 | 1 | 19 | 3 | 3 | 3.75 |
| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 29 | 29 | 11 | 10 | 2.86 | .260 | 1.03 | 6.7 | 2.5 | 5.9 | 195.0 | 146 | 65 | 62 | 20 | 54 | 128 | 4 | 0 | 0 | 2 | 19 | 6 | 2 | 3.94 |
| SP | Mathewson, C.Mathewson, Christy # >> | 29 | 1909 | R | 85 | 29 | 29 | 17 | 7 | 4.14 | .307 | 1.31 | 9.7 | 2.1 | 4.6 | 178.1 | 191 | 86 | 82 | 16 | 42 | 91 | 1 | 0 | 0 | 1 | 17 | 4 | 2 | 3.92 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 28 | 28 | 15 | 5 | 3.73 | .287 | 1.19 | 7.9 | 2.8 | 4.7 | 176.0 | 154 | 76 | 73 | 15 | 55 | 92 | 1 | 0 | 0 | 0 | 19 | 4 | 5 | 4.07 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 30 | 28 | 13 | 7 | 3.42 | .279 | 1.13 | 6.8 | 3.4 | 7.2 | 168.2 | 126 | 65 | 64 | 16 | 64 | 134 | 4 | 1 | 0 | 3 | 18 | 6 | 2 | 3.89 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 73 | 0 | 4 | 3 | 2.75 | .255 | 1.00 | 5.1 | 3.9 | 9.3 | 108.0 | 61 | 34 | 33 | 8 | 47 | 112 | 0 | 10 | 1 | 0 | 0 | 3 | 7 | 3.28 |
| RP | Miller, A.Miller, Andrew † >> | 29 | 2014 | L | 88 | 69 | 0 | 7 | 0 | 1.91 | .257 | 1.03 | 5.8 | 3.5 | 8.5 | 84.2 | 54 | 23 | 18 | 7 | 33 | 79 | 0 | 14 | 2 | 0 | 0 | 1 | 8 | 3.42 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 34 | 0 | 5 | 3 | 2.54 | .273 | 1.05 | 7.2 | 2.3 | 10.2 | 39.0 | 31 | 13 | 11 | 1 | 10 | 44 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 2.08 |
| RP | Radatz, D.Radatz, Dick >> | 27 | 1964 | R | 37 | 10 | 0 | 1 | 0 | 3.54 | .247 | 0.98 | 6.8 | 2.3 | 9.0 | 20.1 | 15 | 10 | 8 | 2 | 5 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.05 |