| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 6 | 15 | 5.85 | .320 | 1.40 | 9.4 | 3.3 | 7.7 | 187.2 | 195 | 127 | 122 | 26 | 68 | 161 | 4 | 0 | 0 | 0 | 11 | 2 | 4 | 4.21 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 27 | 27 | 8 | 11 | 5.03 | .319 | 1.39 | 10.1 | 2.5 | 3.9 | 154.0 | 172 | 94 | 86 | 23 | 42 | 66 | 0 | 0 | 0 | 0 | 12 | 2 | 1 | 4.94 |
| SP | Blue, V.Blue, Vida # $ >> | 22 | 1971 | L | 79 | 27 | 27 | 6 | 18 | 6.27 | .335 | 1.50 | 9.4 | 4.1 | 5.8 | 191.0 | 200 | 143 | 133 | 40 | 87 | 124 | 4 | 0 | 0 | 1 | 5 | 2 | 4 | 5.82 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 27 | 27 | 7 | 13 | 5.90 | .355 | 1.63 | 11.1 | 3.6 | 4.4 | 192.1 | 236 | 135 | 126 | 17 | 77 | 93 | 2 | 0 | 0 | 0 | 6 | 5 | 3 | 4.46 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 56 | 0 | 4 | 2 | 2.21 | .237 | 0.93 | 6.6 | 1.7 | 8.1 | 57.0 | 42 | 14 | 14 | 4 | 11 | 51 | 0 | 33 | 4 | 0 | 0 | 0 | 1 | 2.70 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 72 | 0 | 3 | 4 | 4.86 | .315 | 1.36 | 8.2 | 4.0 | 9.4 | 76.0 | 69 | 41 | 41 | 15 | 34 | 79 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.91 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 75 | 47 | 0 | 4 | 3 | 5.57 | .335 | 1.51 | 10.6 | 3.2 | 9.4 | 51.2 | 60 | 35 | 32 | 9 | 18 | 53 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 4.27 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 39 | 0 | 0 | 1 | 4.43 | .333 | 1.48 | 8.2 | 5.3 | 8.8 | 44.2 | 40 | 22 | 22 | 4 | 26 | 43 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.07 |