| SP | Verlander, J.Verlander, Justin # $ >> | 36 | 2019 | R | 99 | 30 | 30 | 13 | 8 | 4.05 | .280 | 1.15 | 7.8 | 2.6 | 9.2 | 208.2 | 180 | 105 | 94 | 29 | 60 | 213 | 4 | 0 | 0 | 0 | 16 | 3 | 3 | 3.67 |
| SP | Walsh, E.Walsh, Ed † $ >> | 29 | 1910 | R | 93 | 29 | 29 | 17 | 9 | 3.75 | .286 | 1.18 | 8.4 | 2.2 | 4.7 | 225.2 | 210 | 99 | 94 | 25 | 56 | 117 | 15 | 0 | 0 | 2 | 18 | 5 | 4 | 4.22 |
| SP | Cole, G.Cole, Gerrit † >> | 28 | 2019 | R | 91 | 29 | 29 | 17 | 7 | 3.90 | .294 | 1.22 | 7.9 | 3.1 | 8.4 | 196.0 | 172 | 88 | 85 | 20 | 68 | 184 | 2 | 0 | 0 | 0 | 15 | 5 | 3 | 3.57 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 18 | 6 | 4 | 1 | 4.26 | .306 | 1.32 | 9.5 | 2.4 | 3.7 | 93.0 | 98 | 49 | 44 | 10 | 25 | 38 | 2 | 2 | 0 | 0 | 3 | 0 | 4 | 4.39 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 47 | 0 | 3 | 3 | 2.96 | .302 | 1.28 | 7.0 | 4.7 | 8.3 | 54.2 | 42 | 18 | 18 | 4 | 28 | 50 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | 3.72 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 36 | 0 | 4 | 7 | 6.34 | .339 | 1.51 | 10.7 | 3.1 | 9.2 | 38.1 | 45 | 30 | 27 | 8 | 13 | 39 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 4.79 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 24 | 0 | 1 | 2 | 4.03 | .298 | 1.28 | 8.7 | 2.8 | 6.8 | 29.0 | 28 | 14 | 13 | 3 | 9 | 22 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 26 | 0 | 2 | 1 | 3.90 | .274 | 1.13 | 6.3 | 3.9 | 10.2 | 30.0 | 21 | 13 | 13 | 3 | 13 | 34 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.33 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 24 | 21 | 5 | 11 | 6.38 | .342 | 1.55 | 11.3 | 2.6 | 4.5 | 141.0 | 177 | 102 | 100 | 27 | 41 | 71 | 4 | 0 | 0 | 0 | 6 | 2 | 7 | 5.40 |