| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 17 | 17 | 11 | 2 | 3.10 | .268 | 1.06 | 6.3 | 3.2 | 8.6 | 122.0 | 85 | 48 | 42 | 11 | 44 | 116 | 2 | 0 | 0 | 1 | 13 | 5 | 2 | 3.48 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 18 | 18 | 10 | 7 | 4.19 | .290 | 1.19 | 8.9 | 1.8 | 5.7 | 122.1 | 121 | 59 | 57 | 15 | 25 | 77 | 3 | 0 | 0 | 2 | 11 | 4 | 1 | 4.05 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 72 | 17 | 17 | 6 | 7 | 5.28 | .307 | 1.30 | 9.3 | 2.4 | 5.3 | 104.0 | 107 | 63 | 61 | 14 | 28 | 61 | 0 | 0 | 0 | 0 | 8 | 3 | 3 | 4.47 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 17 | 17 | 4 | 9 | 4.77 | .310 | 1.34 | 8.2 | 3.9 | 7.0 | 100.0 | 91 | 55 | 53 | 14 | 43 | 78 | 0 | 0 | 0 | 0 | 9 | 1 | 9 | 4.58 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 16 | 16 | 8 | 6 | 4.00 | .292 | 1.22 | 7.7 | 3.3 | 7.5 | 114.2 | 98 | 51 | 51 | 13 | 42 | 95 | 3 | 0 | 0 | 2 | 8 | 2 | 1 | 3.97 |
| CL | Gossage, R.Gossage, Rich † >> | 30 | 1981 | R | 90 | 36 | 0 | 1 | 2 | 2.36 | .259 | 1.02 | 5.8 | 3.4 | 7.7 | 34.1 | 22 | 9 | 9 | 3 | 13 | 29 | 0 | 23 | 2 | 0 | 0 | 1 | 0 | 3.68 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 39 | 0 | 1 | 2 | 3.52 | .281 | 1.12 | 7.3 | 2.8 | 7.6 | 38.1 | 31 | 18 | 15 | 5 | 12 | 32 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.13 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 39 | 0 | 1 | 2 | 4.15 | .305 | 1.32 | 7.3 | 4.6 | 8.0 | 43.1 | 35 | 20 | 20 | 6 | 22 | 38 | 0 | 2 | 2 | 0 | 0 | 0 | 6 | 4.58 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 30 | 0 | 1 | 2 | 4.11 | .335 | 1.51 | 8.0 | 5.7 | 6.9 | 35.0 | 31 | 17 | 16 | 7 | 22 | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 5.94 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 22 | 0 | 2 | 1 | 8.72 | .420 | 2.17 | 13.3 | 6.9 | 8.6 | 21.2 | 31 | 21 | 21 | 3 | 16 | 20 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.24 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 13 | 0 | 0 | 0 | 6.28 | .348 | 1.60 | 7.7 | 7.1 | 9.0 | 14.1 | 12 | 10 | 10 | 1 | 11 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.29 |