| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 18 | 18 | 10 | 4 | 3.63 | .307 | 1.30 | 7.0 | 4.8 | 8.4 | 101.2 | 78 | 46 | 41 | 6 | 54 | 94 | 0 | 0 | 0 | 0 | 10 | 3 | 2 | 3.60 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 17 | 17 | 7 | 6 | 4.07 | .286 | 1.20 | 8.9 | 1.9 | 4.9 | 115.0 | 114 | 52 | 52 | 15 | 24 | 63 | 2 | 0 | 0 | 1 | 7 | 0 | 1 | 4.23 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 17 | 17 | 8 | 4 | 4.08 | .277 | 1.11 | 6.9 | 3.1 | 7.3 | 106.0 | 81 | 49 | 48 | 12 | 37 | 86 | 1 | 0 | 0 | 1 | 10 | 4 | 2 | 4.01 |
| SP | Reulbach, E.Reulbach, Ed † >> | 24 | 1906 | R | 60 | 17 | 16 | 8 | 2 | 3.05 | .305 | 1.28 | 6.9 | 4.7 | 4.4 | 106.1 | 81 | 41 | 36 | 7 | 55 | 52 | 0 | 0 | 0 | 0 | 10 | 4 | 3 | 4.55 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 48 | 0 | 7 | 1 | 2.98 | .283 | 1.17 | 5.9 | 4.7 | 8.4 | 63.1 | 41 | 25 | 21 | 5 | 33 | 59 | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 3.78 |
| RP | Hoffman, T.Hoffman, Trevor † >> | 31 | 1998 | R | 75 | 46 | 0 | 8 | 0 | 2.30 | .296 | 1.19 | 5.7 | 5.2 | 8.3 | 54.2 | 34 | 14 | 14 | 5 | 31 | 50 | 0 | 2 | 4 | 0 | 0 | 4 | 3 | 4.30 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 34 | 0 | 1 | 0 | 1.98 | .292 | 1.24 | 7.0 | 4.3 | 7.3 | 36.1 | 28 | 11 | 8 | 4 | 17 | 29 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.25 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 29 | 0 | 0 | 0 | 3.92 | .316 | 1.36 | 7.2 | 5.1 | 6.7 | 39.0 | 31 | 18 | 17 | 2 | 22 | 29 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.95 |
| CL | Williams, D.Williams, Devin † >> | 28 | 2023 | R | 73 | 44 | 0 | 4 | 4 | 3.43 | .267 | 1.10 | 5.8 | 4.1 | 10.3 | 42.0 | 27 | 22 | 16 | 4 | 19 | 48 | 0 | 23 | 3 | 0 | 0 | 0 | 2 | 3.31 |