| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 31 | 31 | 11 | 12 | 4.22 | .303 | 1.29 | 8.9 | 2.7 | 4.5 | 234.2 | 231 | 118 | 110 | 20 | 71 | 116 | 4 | 0 | 0 | 2 | 15 | 4 | 4 | 4.08 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 30 | 30 | 11 | 12 | 4.31 | .311 | 1.34 | 8.8 | 3.3 | 6.4 | 221.1 | 215 | 109 | 106 | 26 | 82 | 156 | 6 | 0 | 0 | 2 | 15 | 3 | 5 | 4.27 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 60 | 30 | 30 | 8 | 12 | 5.12 | .337 | 1.47 | 8.1 | 5.2 | 8.0 | 175.2 | 158 | 104 | 100 | 21 | 101 | 155 | 0 | 0 | 0 | 0 | 15 | 9 | 3 | 4.67 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 29 | 29 | 7 | 12 | 6.87 | .362 | 1.68 | 10.9 | 4.3 | 5.9 | 165.0 | 200 | 130 | 126 | 32 | 78 | 108 | 1 | 0 | 0 | 0 | 7 | 3 | 7 | 5.68 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 87 | 0 | 9 | 6 | 3.21 | .306 | 1.31 | 8.3 | 3.6 | 7.6 | 134.2 | 123 | 53 | 48 | 11 | 54 | 113 | 0 | 8 | 6 | 0 | 0 | 1 | 0 | 3.61 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 75 | 0 | 6 | 3 | 3.00 | .250 | 0.99 | 7.2 | 1.7 | 8.6 | 90.0 | 72 | 33 | 30 | 11 | 17 | 86 | 0 | 9 | 5 | 0 | 0 | 1 | 1 | 3.28 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 30 | 0 | 3 | 2 | 3.17 | .289 | 1.18 | 6.8 | 3.9 | 7.9 | 48.1 | 36 | 17 | 17 | 6 | 21 | 42 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 4.31 |