| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 16 | 16 | 7 | 3 | 2.65 | .243 | 0.96 | 5.9 | 2.7 | 9.9 | 112.0 | 74 | 35 | 33 | 8 | 33 | 123 | 0 | 0 | 0 | 0 | 12 | 1 | 0 | 2.64 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 16 | 16 | 5 | 5 | 4.93 | .313 | 1.36 | 9.5 | 2.8 | 8.5 | 98.2 | 103 | 58 | 54 | 18 | 31 | 93 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 4.47 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 15 | 15 | 4 | 8 | 5.90 | .321 | 1.41 | 9.8 | 3.0 | 3.5 | 100.2 | 109 | 68 | 66 | 14 | 33 | 39 | 3 | 0 | 0 | 0 | 4 | 1 | 0 | 5.06 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 15 | 15 | 6 | 8 | 6.30 | .353 | 1.61 | 12.0 | 2.6 | 4.4 | 85.2 | 113 | 63 | 60 | 13 | 25 | 42 | 2 | 0 | 0 | 0 | 7 | 2 | 0 | 4.95 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 33 | 0 | 2 | 6 | 2.88 | .295 | 1.22 | 7.7 | 3.4 | 7.1 | 34.1 | 29 | 11 | 11 | 3 | 13 | 27 | 0 | 15 | 0 | 0 | 0 | 1 | 0 | 3.79 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 93 | 34 | 0 | 4 | 0 | 3.41 | .288 | 1.19 | 6.3 | 4.4 | 10.2 | 37.0 | 26 | 14 | 14 | 3 | 18 | 42 | 0 | 4 | 0 | 0 | 0 | 1 | 2 | 3.32 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 37 | 0 | 0 | 3 | 4.57 | .354 | 1.62 | 11.6 | 3.1 | 6.8 | 41.1 | 53 | 21 | 21 | 5 | 14 | 31 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 4.17 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 18 | 0 | 2 | 1 | 3.32 | .323 | 1.43 | 6.9 | 6.4 | 8.6 | 21.2 | 16 | 8 | 8 | 1 | 15 | 20 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.86 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 15 | 0 | 0 | 0 | 1.89 | .240 | 0.89 | 4.7 | 3.3 | 7.1 | 19.0 | 10 | 4 | 4 | 1 | 7 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.37 |