| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 31 | 31 | 12 | 11 | 4.20 | .293 | 1.23 | 8.8 | 2.3 | 8.7 | 214.1 | 209 | 105 | 100 | 31 | 55 | 206 | 2 | 0 | 0 | 0 | 19 | 2 | 3 | 3.76 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 31 | 31 | 7 | 12 | 4.57 | .325 | 1.42 | 9.4 | 3.4 | 7.4 | 210.2 | 220 | 111 | 107 | 32 | 79 | 173 | 2 | 0 | 0 | 0 | 18 | 5 | 7 | 4.53 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 56 | 31 | 29 | 10 | 13 | 5.14 | .337 | 1.50 | 9.9 | 3.6 | 3.8 | 191.0 | 210 | 116 | 109 | 20 | 76 | 80 | 4 | 0 | 0 | 0 | 15 | 5 | 1 | 4.80 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 85 | 0 | 6 | 11 | 4.56 | .321 | 1.41 | 8.9 | 3.8 | 9.2 | 108.2 | 107 | 57 | 55 | 17 | 46 | 110 | 0 | 8 | 7 | 0 | 0 | 1 | 4 | 4.31 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 79 | 0 | 5 | 6 | 3.53 | .285 | 1.14 | 8.6 | 1.7 | 7.7 | 94.1 | 90 | 41 | 37 | 11 | 18 | 80 | 0 | 10 | 4 | 0 | 0 | 5 | 0 | 3.55 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 44 | 0 | 1 | 3 | 5.07 | .355 | 1.61 | 9.4 | 5.3 | 8.8 | 49.2 | 51 | 32 | 28 | 8 | 29 | 48 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 5.06 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 44 | 0 | 1 | 3 | 2.29 | .282 | 1.14 | 5.6 | 4.6 | 9.0 | 51.0 | 32 | 13 | 13 | 2 | 26 | 51 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.16 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 39 | 0 | 4 | 1 | 3.07 | .283 | 1.16 | 7.0 | 3.5 | 10.0 | 44.0 | 34 | 15 | 15 | 6 | 17 | 49 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.77 |