| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 31 | 31 | 14 | 11 | 3.04 | .275 | 1.13 | 7.8 | 2.4 | 7.4 | 183.2 | 159 | 72 | 62 | 18 | 48 | 150 | 0 | 0 | 0 | 0 | 21 | 2 | 4 | 3.46 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 31 | 31 | 18 | 4 | 2.86 | .265 | 1.07 | 7.1 | 2.6 | 4.8 | 223.2 | 175 | 77 | 71 | 16 | 64 | 119 | 4 | 0 | 0 | 1 | 21 | 3 | 4 | 3.77 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 30 | 30 | 14 | 9 | 4.67 | .290 | 1.22 | 9.0 | 2.0 | 8.1 | 179.1 | 179 | 96 | 93 | 25 | 39 | 162 | 3 | 0 | 0 | 1 | 14 | 2 | 3 | 3.69 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 29 | 29 | 18 | 5 | 3.38 | .280 | 1.16 | 7.2 | 3.2 | 6.8 | 192.0 | 154 | 72 | 72 | 12 | 68 | 145 | 2 | 0 | 0 | 1 | 20 | 2 | 5 | 3.40 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 74 | 0 | 1 | 2 | 3.34 | .279 | 1.14 | 6.7 | 3.6 | 11.3 | 86.1 | 64 | 35 | 32 | 8 | 34 | 108 | 0 | 15 | 2 | 0 | 0 | 2 | 2 | 2.95 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 44 | 0 | 4 | 1 | 3.38 | .298 | 1.25 | 6.6 | 4.7 | 7.7 | 48.0 | 35 | 20 | 18 | 1 | 25 | 41 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.19 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 35 | 0 | 7 | 4 | 6.12 | .378 | 1.79 | 10.4 | 5.9 | 7.3 | 32.1 | 37 | 22 | 22 | 4 | 21 | 26 | 0 | 5 | 2 | 0 | 0 | 1 | 5 | 5.06 |
| RP | Eichhorn, M.Eichhorn, Mark # >> | 26 | 1986 | R | 48 | 32 | 0 | 4 | 2 | 4.39 | .296 | 1.25 | 8.6 | 2.8 | 7.1 | 65.2 | 62 | 34 | 32 | 8 | 20 | 51 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.00 |