| SP | Buehler, W.Buehler, Walker # >> | 23 | 2018 | R | 85 | 24 | 24 | 1 | 9 | 4.83 | .322 | 1.41 | 8.1 | 4.6 | 8.2 | 138.0 | 124 | 75 | 74 | 22 | 70 | 125 | 0 | 0 | 0 | 0 | 11 | 3 | 4 | 4.85 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 23 | 23 | 11 | 6 | 2.92 | .304 | 1.28 | 7.3 | 4.2 | 8.9 | 157.0 | 128 | 59 | 51 | 17 | 73 | 155 | 2 | 0 | 0 | 0 | 17 | 5 | 4 | 3.92 |
| SP | Flaherty, J.Flaherty, Jack # >> | 23 | 2019 | R | 82 | 23 | 23 | 9 | 5 | 4.49 | .311 | 1.34 | 9.6 | 2.4 | 9.9 | 126.1 | 135 | 63 | 63 | 18 | 34 | 138 | 0 | 0 | 0 | 0 | 12 | 2 | 2 | 3.52 |
| SP | Dickey, R.Dickey, R.A. >> | 38 | 2012 | R | 42 | 23 | 23 | 11 | 1 | 3.76 | .317 | 1.38 | 9.1 | 3.3 | 8.2 | 124.1 | 125 | 52 | 52 | 16 | 46 | 113 | 0 | 0 | 0 | 0 | 13 | 2 | 1 | 4.02 |
| SP | Messersmith, A.Messersmith, Andy >> | 30 | 1975 | R | 43 | 23 | 22 | 8 | 10 | 4.83 | .313 | 1.35 | 8.2 | 4.0 | 6.8 | 147.1 | 134 | 82 | 79 | 24 | 65 | 111 | 6 | 1 | 0 | 0 | 10 | 2 | 4 | 4.98 |
| RP | Miller, A.Miller, Andrew # >> | 29 | 2014 | L | 87 | 65 | 0 | 8 | 4 | 4.07 | .286 | 1.19 | 7.5 | 3.2 | 11.6 | 84.0 | 70 | 39 | 38 | 11 | 30 | 108 | 0 | 2 | 4 | 0 | 0 | 1 | 6 | 3.24 |
| SU | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 54 | 0 | 1 | 3 | 2.93 | .267 | 1.08 | 7.7 | 2.1 | 12.5 | 61.1 | 52 | 20 | 20 | 6 | 14 | 85 | 0 | 2 | 4 | 0 | 0 | 1 | 2 | 2.23 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 62 | 0 | 5 | 6 | 3.83 | .278 | 1.15 | 8.6 | 1.8 | 8.7 | 84.2 | 80 | 36 | 36 | 14 | 17 | 81 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 3.88 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 60 | 0 | 4 | 5 | 3.94 | .302 | 1.26 | 7.5 | 4.0 | 6.6 | 61.2 | 51 | 27 | 27 | 9 | 27 | 45 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.87 |
| CL | Doolittle, S.Doolittle, Sean # >> | 31 | 2018 | L | 98 | 46 | 0 | 1 | 7 | 3.88 | .287 | 1.19 | 8.6 | 2.2 | 7.4 | 46.1 | 44 | 20 | 20 | 9 | 11 | 38 | 0 | 24 | 5 | 0 | 0 | 1 | 1 | 4.67 |