| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 8 | 8 | 4 | 2 | 3.48 | .276 | 1.08 | 6.5 | 3.4 | 10.1 | 51.2 | 37 | 20 | 20 | 4 | 19 | 57 | 1 | 0 | 0 | 0 | 6 | 3 | 1 | 3.08 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 8 | 8 | 4 | 3 | 4.62 | .315 | 1.36 | 8.4 | 3.9 | 9.0 | 48.2 | 45 | 28 | 25 | 7 | 21 | 48 | 1 | 0 | 0 | 1 | 5 | 1 | 1 | 4.27 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 16 | 0 | 1 | 3 | 5.52 | .343 | 1.57 | 7.1 | 7.7 | 9.6 | 14.2 | 11 | 9 | 9 | 3 | 12 | 15 | 0 | 7 | 2 | 0 | 0 | 0 | 1 | 6.21 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 21 | 0 | 1 | 0 | 1.97 | .213 | 0.78 | 3.9 | 3.1 | 10.1 | 32.0 | 14 | 7 | 7 | 5 | 11 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.91 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 24 | 0 | 1 | 2 | 2.20 | .277 | 1.15 | 7.4 | 3.2 | 10.0 | 28.2 | 23 | 8 | 7 | 1 | 10 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.32 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 18 | 0 | 0 | 0 | 1.35 | .250 | 1.00 | 5.4 | 3.6 | 10.4 | 20.0 | 12 | 3 | 3 | 2 | 8 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.20 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 10 | 0 | 1 | 0 | 0.79 | .150 | 0.53 | 3.3 | 1.6 | 9.0 | 11.1 | 4 | 1 | 1 | 0 | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.55 |