| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 90 | 23 | 23 | 13 | 8 | 3.17 | .290 | 1.21 | 8.4 | 2.5 | 7.3 | 150.1 | 140 | 53 | 53 | 10 | 42 | 121 | 6 | 0 | 0 | 2 | 16 | 2 | 1 | 3.13 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 94 | 56 | 0 | 3 | 1 | 2.08 | .242 | 0.94 | 5.0 | 3.5 | 10.6 | 56.1 | 31 | 13 | 13 | 5 | 22 | 66 | 0 | 33 | 4 | 0 | 0 | 1 | 0 | 3.04 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 61 | 0 | 3 | 3 | 4.61 | .319 | 1.39 | 10.7 | 1.9 | 9.8 | 68.1 | 81 | 38 | 35 | 12 | 14 | 74 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.78 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 52 | 0 | 5 | 4 | 5.01 | .345 | 1.56 | 6.7 | 7.5 | 10.8 | 55.2 | 41 | 37 | 31 | 7 | 46 | 66 | 0 | 1 | 4 | 0 | 0 | 1 | 1 | 4.82 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 31 | 0 | 3 | 0 | 3.18 | .306 | 1.29 | 6.9 | 4.8 | 7.4 | 34.0 | 26 | 18 | 12 | 4 | 18 | 28 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.56 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 30 | 0 | 1 | 1 | 4.17 | .304 | 1.28 | 8.3 | 3.5 | 11.0 | 36.2 | 33 | 17 | 17 | 6 | 14 | 44 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.97 |