| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 32 | 32 | 11 | 8 | 3.54 | .277 | 1.12 | 7.1 | 3.0 | 8.2 | 213.1 | 169 | 87 | 84 | 24 | 70 | 195 | 2 | 0 | 0 | 0 | 20 | 6 | 3 | 3.70 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 32 | 32 | 16 | 14 | 3.70 | .285 | 1.19 | 8.3 | 2.5 | 5.0 | 218.2 | 201 | 93 | 90 | 23 | 60 | 122 | 11 | 0 | 0 | 2 | 21 | 1 | 1 | 4.09 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 31 | 30 | 13 | 14 | 4.73 | .321 | 1.40 | 7.6 | 5.0 | 4.0 | 192.1 | 162 | 108 | 101 | 18 | 107 | 85 | 3 | 0 | 0 | 1 | 13 | 4 | 4 | 5.07 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 9 | 9 | 2 | 5 | 5.84 | .313 | 1.37 | 10.4 | 2.0 | 6.1 | 44.2 | 51 | 29 | 29 | 7 | 10 | 30 | 1 | 0 | 0 | 1 | 2 | 0 | 2 | 4.39 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 89 | 0 | 5 | 2 | 2.49 | .276 | 1.11 | 6.4 | 3.6 | 8.5 | 115.2 | 82 | 32 | 32 | 10 | 46 | 108 | 0 | 5 | 1 | 0 | 0 | 4 | 8 | 3.56 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 60 | 0 | 5 | 1 | 2.94 | .271 | 1.10 | 6.5 | 3.5 | 8.5 | 79.2 | 57 | 26 | 26 | 8 | 31 | 75 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 3.63 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 49 | 0 | 3 | 4 | 3.03 | .278 | 1.12 | 7.1 | 3.0 | 8.3 | 62.1 | 49 | 22 | 21 | 5 | 21 | 57 | 0 | 6 | 0 | 0 | 0 | 2 | 5 | 3.32 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 37 | 0 | 3 | 1 | 2.74 | .289 | 1.20 | 5.6 | 5.4 | 9.4 | 42.2 | 26 | 13 | 13 | 1 | 25 | 44 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 3.07 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 19 | 0 | 1 | 2 | 3.96 | .330 | 1.44 | 7.2 | 5.8 | 10.1 | 25.0 | 20 | 13 | 11 | 2 | 16 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 3.84 |