| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 11 | 11 | 6 | 3 | 3.66 | .298 | 1.27 | 8.5 | 3.0 | 6.3 | 76.1 | 72 | 40 | 31 | 5 | 25 | 53 | 2 | 0 | 0 | 1 | 6 | 0 | 2 | 3.45 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 17 | 16 | 10 | 6 | 4.08 | .305 | 1.31 | 9.1 | 2.8 | 5.2 | 108.0 | 109 | 51 | 49 | 10 | 33 | 62 | 1 | 0 | 0 | 1 | 9 | 0 | 3 | 3.97 |
| SP | Walsh, E.Walsh, Ed † $$ >> | 29 | 1910 | R | 93 | 18 | 18 | 9 | 7 | 3.15 | .255 | 1.03 | 6.8 | 2.4 | 6.0 | 125.2 | 95 | 44 | 44 | 12 | 34 | 84 | 8 | 0 | 0 | 2 | 12 | 0 | 2 | 3.72 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 9 | 7 | 2 | 2 | 5.08 | .296 | 1.26 | 8.8 | 2.7 | 3.9 | 44.1 | 43 | 27 | 25 | 5 | 13 | 19 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 4.50 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 16 | 16 | 4 | 7 | 5.26 | .295 | 1.24 | 8.9 | 2.3 | 8.6 | 90.2 | 89 | 53 | 53 | 11 | 23 | 86 | 3 | 0 | 0 | 1 | 7 | 2 | 0 | 3.51 |
| SU | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 31 | 0 | 1 | 1 | 3.77 | .262 | 1.06 | 5.8 | 3.8 | 10.5 | 31.0 | 20 | 13 | 13 | 1 | 13 | 36 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.35 |
| CL | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 33 | 0 | 1 | 1 | 3.65 | .323 | 1.43 | 8.5 | 4.4 | 9.0 | 37.0 | 35 | 15 | 15 | 3 | 18 | 37 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.51 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 29 | 0 | 0 | 1 | 4.66 | .286 | 1.20 | 7.8 | 3.3 | 9.0 | 36.2 | 31 | 19 | 19 | 6 | 13 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.25 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 26 | 0 | 1 | 1 | 5.02 | .323 | 1.40 | 8.4 | 4.5 | 8.7 | 28.2 | 26 | 16 | 16 | 3 | 14 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.07 |
| RP | Hiller, J.Hiller, John >> | 30 | 1973 | L | 26 | 13 | 0 | 0 | 0 | 5.40 | .417 | 2.14 | 13.1 | 7.4 | 7.4 | 11.2 | 16 | 7 | 7 | 2 | 9 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.18 |
| SP | Hubbell, C.Hubbell, Carl >> | 30 | 1933 | L | 36 | 13 | 4 | 2 | 3 | 6.25 | .377 | 1.79 | 13.9 | 2.5 | 4.7 | 44.2 | 68 | 37 | 31 | 7 | 12 | 23 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.91 |