| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 28 | 28 | 13 | 11 | 4.13 | .305 | 1.28 | 9.0 | 2.5 | 5.4 | 205.0 | 204 | 101 | 94 | 25 | 58 | 122 | 9 | 0 | 0 | 1 | 15 | 8 | 2 | 4.36 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 27 | 27 | 9 | 14 | 4.79 | .292 | 1.23 | 7.2 | 3.8 | 4.7 | 178.1 | 143 | 97 | 95 | 32 | 76 | 93 | 9 | 0 | 0 | 2 | 11 | 2 | 16 | 5.61 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 25 | 25 | 10 | 13 | 4.61 | .320 | 1.40 | 8.0 | 4.6 | 4.7 | 164.0 | 146 | 86 | 84 | 20 | 83 | 86 | 3 | 0 | 0 | 1 | 14 | 3 | 4 | 5.11 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 24 | 24 | 4 | 14 | 7.86 | .366 | 1.71 | 11.4 | 4.0 | 5.5 | 123.2 | 156 | 109 | 108 | 32 | 55 | 75 | 0 | 0 | 0 | 0 | 8 | 3 | 7 | 6.58 |
| RP | Benoit, J.Benoit, Joaquin # >> | 33 | 2010 | R | 95 | 68 | 0 | 2 | 5 | 5.28 | .321 | 1.34 | 9.7 | 2.4 | 9.6 | 90.1 | 97 | 53 | 53 | 16 | 24 | 96 | 0 | 9 | 3 | 0 | 0 | 7 | 1 | 4.21 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 49 | 0 | 3 | 2 | 4.91 | .342 | 1.56 | 9.3 | 4.8 | 5.7 | 62.1 | 64 | 41 | 34 | 7 | 33 | 39 | 0 | 4 | 2 | 0 | 0 | 0 | 1 | 4.81 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 41 | 0 | 1 | 3 | 5.48 | .360 | 1.69 | 10.9 | 4.5 | 9.0 | 42.2 | 51 | 30 | 26 | 10 | 21 | 42 | 0 | 1 | 3 | 0 | 0 | 0 | 4 | 5.60 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 45 | 35 | 0 | 2 | 2 | 4.57 | .309 | 1.32 | 7.5 | 4.4 | 9.2 | 43.1 | 36 | 22 | 22 | 4 | 21 | 44 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 3.70 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 17 | 2 | 2 | 0 | 5.13 | .333 | 1.50 | 8.2 | 5.5 | 4.6 | 33.1 | 30 | 19 | 19 | 7 | 20 | 17 | 0 | 1 | 1 | 0 | 2 | 0 | 1 | 6.55 |