| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 11 | 10 | 4.56 | .314 | 1.36 | 8.7 | 3.5 | 8.4 | 173.2 | 168 | 95 | 88 | 19 | 68 | 161 | 3 | 0 | 0 | 1 | 14 | 2 | 3 | 3.78 |
| SP | Scott, M.Scott, Mike $ >> | 31 | 1986 | R | 87 | 27 | 27 | 11 | 10 | 5.38 | .332 | 1.47 | 10.0 | 3.3 | 8.0 | 152.1 | 169 | 91 | 91 | 26 | 55 | 135 | 2 | 0 | 0 | 0 | 11 | 3 | 3 | 4.59 |
| SP | Adams, B.Adams, Babe # $ >> | 27 | 1909 | R | 86 | 27 | 26 | 5 | 14 | 6.92 | .361 | 1.65 | 11.3 | 3.5 | 4.8 | 117.0 | 147 | 95 | 90 | 19 | 46 | 63 | 0 | 0 | 0 | 0 | 8 | 5 | 2 | 5.34 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 26 | 26 | 11 | 3 | 3.98 | .287 | 1.20 | 8.0 | 2.8 | 7.5 | 167.1 | 149 | 75 | 74 | 19 | 52 | 140 | 3 | 0 | 0 | 1 | 14 | 1 | 2 | 3.75 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 27 | 26 | 7 | 12 | 5.60 | .329 | 1.44 | 10.0 | 3.0 | 5.0 | 143.0 | 159 | 96 | 89 | 20 | 47 | 79 | 4 | 0 | 0 | 0 | 11 | 4 | 1 | 4.78 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 64 | 0 | 0 | 6 | 2.92 | .281 | 1.18 | 7.3 | 3.4 | 8.6 | 64.2 | 52 | 23 | 21 | 6 | 24 | 61 | 0 | 36 | 5 | 0 | 0 | 0 | 1 | 3.44 |
| SU | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 49 | 0 | 2 | 3 | 4.47 | .282 | 1.18 | 8.8 | 1.8 | 8.7 | 54.1 | 53 | 27 | 27 | 10 | 11 | 52 | 0 | 1 | 6 | 0 | 0 | 0 | 1 | 4.09 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 62 | 0 | 7 | 4 | 4.58 | .260 | 1.04 | 6.8 | 2.7 | 10.2 | 76.2 | 57 | 39 | 39 | 14 | 23 | 86 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.08 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 43 | 0 | 2 | 2 | 3.91 | .290 | 1.19 | 7.5 | 3.2 | 4.9 | 53.0 | 44 | 26 | 23 | 5 | 19 | 29 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 4.32 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 30 | 36 | 0 | 1 | 2 | 4.47 | .272 | 1.12 | 6.8 | 3.3 | 5.1 | 46.1 | 35 | 23 | 23 | 3 | 17 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.83 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 31 | 0 | 6 | 4 | 3.29 | .306 | 1.31 | 8.5 | 3.3 | 4.1 | 142.1 | 134 | 55 | 52 | 10 | 52 | 64 | 0 | 1 | 0 | 0 | 0 | 2 | 5 | 4.15 |