| SP | Tiant, L.Tiant, Luis # $ >> | 28 | 1968 | R | 97 | 18 | 18 | 6 | 8 | 3.62 | .294 | 1.22 | 7.7 | 3.3 | 8.0 | 112.0 | 96 | 48 | 45 | 8 | 41 | 99 | 1 | 0 | 0 | 0 | 10 | 3 | 3 | 3.34 |
| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 94 | 17 | 17 | 5 | 7 | 5.72 | .320 | 1.36 | 9.0 | 3.3 | 6.3 | 94.1 | 94 | 66 | 60 | 17 | 34 | 66 | 0 | 0 | 0 | 0 | 8 | 5 | 3 | 5.19 |
| SP | Cole, G.Cole, Gerrit $$ >> | 28 | 2019 | R | 92 | 18 | 17 | 6 | 7 | 4.35 | .332 | 1.49 | 8.8 | 4.6 | 8.3 | 99.1 | 97 | 54 | 48 | 12 | 51 | 91 | 0 | 0 | 0 | 0 | 10 | 0 | 2 | 4.28 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 16 | 16 | 3 | 7 | 4.99 | .312 | 1.36 | 9.2 | 3.1 | 5.3 | 95.2 | 97 | 53 | 53 | 14 | 33 | 56 | 3 | 0 | 0 | 0 | 6 | 0 | 1 | 4.78 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 16 | 16 | 3 | 9 | 6.50 | .345 | 1.58 | 9.8 | 4.6 | 7.3 | 81.2 | 88 | 60 | 59 | 13 | 41 | 66 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 4.98 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 47 | 0 | 2 | 6 | 2.72 | .254 | 1.00 | 7.0 | 2.0 | 9.7 | 53.0 | 41 | 19 | 16 | 5 | 12 | 57 | 0 | 18 | 2 | 0 | 0 | 1 | 1 | 2.81 |
| SU | Nathan, J.Nathan, Joe $ >> | 32 | 2006 | R | 87 | 43 | 0 | 2 | 0 | 2.08 | .257 | 0.98 | 5.4 | 3.5 | 6.6 | 52.0 | 31 | 15 | 12 | 7 | 20 | 38 | 0 | 3 | 4 | 0 | 0 | 3 | 1 | 4.62 |
| RP | Benitez, A.Benitez, Armando $$ >> | 32 | 2004 | R | 82 | 52 | 0 | 3 | 3 | 3.84 | .320 | 1.38 | 7.8 | 4.6 | 5.2 | 68.0 | 59 | 32 | 29 | 8 | 35 | 39 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 5.01 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 79 | 42 | 0 | 2 | 2 | 3.81 | .312 | 1.36 | 9.3 | 3.0 | 9.0 | 54.1 | 56 | 26 | 23 | 6 | 18 | 54 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.44 |