| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 18 | 18 | 6 | 8 | 3.69 | .295 | 1.23 | 8.4 | 2.7 | 8.8 | 124.1 | 116 | 57 | 51 | 24 | 37 | 121 | 1 | 0 | 0 | 0 | 11 | 3 | 0 | 4.53 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 83 | 17 | 17 | 7 | 9 | 4.92 | .301 | 1.27 | 10.0 | 1.5 | 5.3 | 117.0 | 130 | 68 | 64 | 17 | 19 | 69 | 4 | 0 | 0 | 1 | 6 | 2 | 4 | 4.25 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 17 | 17 | 5 | 8 | 5.87 | .351 | 1.59 | 10.5 | 3.9 | 4.4 | 104.1 | 121 | 69 | 68 | 12 | 45 | 51 | 2 | 0 | 0 | 1 | 5 | 3 | 1 | 4.90 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 45 | 0 | 2 | 2 | 4.16 | .304 | 1.31 | 7.7 | 4.2 | 9.0 | 67.0 | 57 | 34 | 31 | 8 | 31 | 67 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 3.94 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 34 | 0 | 4 | 1 | 3.43 | .236 | 0.93 | 6.6 | 1.7 | 8.1 | 42.0 | 31 | 16 | 16 | 6 | 8 | 38 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.62 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 27 | 0 | 3 | 1 | 3.33 | .263 | 1.05 | 6.2 | 3.4 | 5.1 | 48.2 | 33 | 22 | 18 | 5 | 18 | 27 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.42 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 17 | 0 | 0 | 0 | 6.29 | .360 | 1.60 | 9.8 | 4.9 | 7.9 | 24.1 | 26 | 18 | 17 | 5 | 13 | 21 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.83 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 2 | 0 | 0 | 0 | 0.00 | .286 | 1.20 | 9.0 | 9.0 | 0.0 | 1.2 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |