| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 28 | 28 | 13 | 14 | 4.44 | .294 | 1.22 | 8.0 | 3.0 | 8.4 | 178.1 | 159 | 92 | 88 | 26 | 59 | 166 | 3 | 0 | 0 | 0 | 16 | 5 | 3 | 4.11 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 28 | 28 | 9 | 14 | 5.22 | .308 | 1.32 | 8.8 | 3.2 | 9.5 | 148.1 | 144 | 88 | 86 | 23 | 52 | 157 | 1 | 0 | 0 | 1 | 13 | 2 | 1 | 3.99 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 26 | 26 | 11 | 13 | 4.17 | .303 | 1.29 | 8.9 | 2.7 | 4.7 | 174.2 | 173 | 91 | 81 | 18 | 53 | 91 | 1 | 0 | 0 | 0 | 15 | 2 | 7 | 4.25 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 27 | 26 | 10 | 11 | 5.85 | .333 | 1.46 | 10.3 | 2.9 | 5.8 | 147.2 | 169 | 101 | 96 | 25 | 47 | 94 | 3 | 0 | 0 | 0 | 10 | 5 | 1 | 4.99 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 59 | 0 | 2 | 5 | 2.86 | .244 | 0.97 | 7.2 | 1.5 | 9.3 | 66.0 | 53 | 22 | 21 | 8 | 11 | 68 | 0 | 26 | 2 | 0 | 0 | 0 | 0 | 3.02 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 68 | 0 | 1 | 1 | 4.05 | .306 | 1.31 | 7.2 | 4.7 | 10.8 | 73.1 | 58 | 38 | 33 | 10 | 38 | 88 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.97 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 46 | 0 | 4 | 2 | 3.29 | .314 | 1.37 | 8.3 | 4.2 | 8.8 | 54.2 | 50 | 23 | 20 | 7 | 25 | 53 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.11 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 39 | 0 | 2 | 1 | 5.56 | .382 | 1.81 | 10.2 | 6.2 | 13.4 | 45.1 | 51 | 28 | 28 | 8 | 31 | 67 | 0 | 1 | 0 | 0 | 0 | 2 | 6 | 4.53 |