| SP | Holmes, C.Holmes, Clay >> | 32 | 2025 | R | 46 | 35 | 34 | 11 | 12 | 3.66 | .316 | 1.35 | 7.9 | 4.3 | 7.3 | 182.0 | 159 | 76 | 74 | 14 | 86 | 147 | 0 | 0 | 0 | 0 | 10 | 7 | 0 | 3.92 |
| SP | Springs, J.Springs, Jeffrey >> | 32 | 2025 | L | 66 | 17 | 17 | 3 | 10 | 3.70 | .264 | 1.03 | 7.0 | 2.3 | 8.5 | 97.1 | 75 | 43 | 40 | 11 | 25 | 92 | 0 | 0 | 0 | 0 | 9 | 5 | 0 | 3.51 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 67 | 32 | 32 | 9 | 14 | 4.23 | .308 | 1.32 | 9.9 | 2.0 | 8.1 | 198.0 | 217 | 96 | 93 | 31 | 44 | 178 | 2 | 0 | 0 | 1 | 16 | 4 | 5 | 3.96 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 52 | 27 | 26 | 8 | 10 | 4.95 | .326 | 1.42 | 9.5 | 3.3 | 7.6 | 151.0 | 160 | 85 | 83 | 17 | 55 | 127 | 0 | 0 | 0 | 0 | 12 | 4 | 2 | 3.95 |
| RP | Little, B.Little, Brendon >> | 28 | 2025 | L | 65 | 101 | 0 | 5 | 2 | 2.29 | .287 | 1.18 | 7.3 | 3.4 | 10.5 | 98.1 | 79 | 29 | 25 | 7 | 37 | 114 | 0 | 3 | 2 | 0 | 0 | 3 | 7 | 2.83 |
| RP | Santillan, T.Santillan, Tony >> | 28 | 2025 | R | 81 | 92 | 0 | 3 | 4 | 4.03 | .289 | 1.21 | 7.6 | 3.3 | 10.6 | 98.1 | 83 | 48 | 44 | 17 | 36 | 115 | 0 | 0 | 3 | 0 | 0 | 1 | 6 | 4.04 |
| RP | Flexen, C.Flexen, Christopher >> | 30 | 2025 | R | 63 | 49 | 0 | 3 | 1 | 3.75 | .294 | 1.22 | 8.9 | 2.2 | 7.3 | 69.2 | 68 | 29 | 29 | 8 | 17 | 56 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 3.71 |
| CL | Jansen, K.Jansen, Kenley † >> | 37 | 2025 | R | 92 | 67 | 0 | 5 | 7 | 2.74 | .263 | 1.06 | 6.6 | 3.0 | 6.8 | 75.2 | 55 | 23 | 23 | 9 | 25 | 57 | 0 | 30 | 3 | 0 | 0 | 1 | 0 | 4.08 |
| SP | Morales, L.Morales, Luis >> | 22 | 2025 | R | 79 | 15 | 9 | 1 | 6 | 6.28 | .358 | 1.65 | 10.0 | 4.8 | 8.0 | 43.0 | 48 | 31 | 30 | 12 | 23 | 38 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 6.53 |