| SP | Kluber, C.Kluber, Corey >> | 30 | 2016 | R | 97 | 20 | 20 | 9 | 5 | 4.76 | .335 | 1.46 | 10.0 | 3.1 | 11.6 | 121.0 | 135 | 64 | 64 | 14 | 42 | 156 | 0 | 0 | 0 | 0 | 9 | 6 | 4 | 3.12 |
| SP | Syndergaard, N.Syndergaard, Noah >> | 23 | 2016 | R | 89 | 21 | 20 | 10 | 4 | 2.95 | .298 | 1.19 | 8.4 | 2.4 | 11.2 | 125.0 | 116 | 47 | 41 | 10 | 33 | 156 | 0 | 0 | 0 | 0 | 13 | 10 | 5 | 2.58 |
| SP | Griffin, A.Griffin, A.J. >> | 28 | 2016 | R | 55 | 18 | 18 | 4 | 8 | 5.68 | .341 | 1.53 | 10.0 | 3.8 | 8.0 | 90.1 | 100 | 58 | 57 | 15 | 38 | 80 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 4.72 |
| SP | Iwakuma, H.Iwakuma, Hisashi >> | 35 | 2016 | R | 43 | 15 | 15 | 4 | 5 | 5.52 | .323 | 1.40 | 10.6 | 2.1 | 7.6 | 91.1 | 107 | 57 | 56 | 16 | 21 | 77 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 4.38 |
| CL | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 100 | 34 | 0 | 3 | 4 | 2.70 | .236 | 0.93 | 4.8 | 3.8 | 11.5 | 36.2 | 19 | 12 | 11 | 5 | 15 | 46 | 0 | 18 | 3 | 0 | 0 | 0 | 3 | 3.50 |
| SU | Phelps, D.Phelps, David >> | 29 | 2016 | R | 87 | 50 | 0 | 2 | 1 | 1.61 | .267 | 1.06 | 5.5 | 4.1 | 10.6 | 61.1 | 37 | 11 | 11 | 3 | 28 | 72 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 2.75 |
| RP | Familia, J.Familia, Jeurys >> | 26 | 2016 | R | 73 | 53 | 0 | 1 | 1 | 3.39 | .297 | 1.25 | 7.9 | 3.4 | 10.4 | 58.1 | 51 | 22 | 22 | 6 | 22 | 67 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.22 |
| RP | Ohlendorf, R.Ohlendorf, Ross >> | 34 | 2016 | R | 45 | 33 | 0 | 5 | 0 | 4.86 | .331 | 1.43 | 7.5 | 5.4 | 10.9 | 37.0 | 31 | 21 | 20 | 5 | 22 | 45 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.27 |
| RP | Barnes, M.Barnes, Matt >> | 26 | 2016 | R | 42 | 29 | 0 | 1 | 2 | 2.97 | .238 | 0.94 | 6.8 | 1.8 | 10.5 | 36.1 | 27 | 12 | 12 | 4 | 7 | 42 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.69 |