| SP | Hamels, C.Hamels, Cole † >> | 29 | 2012 | L | 94 | 25 | 25 | 17 | 2 | 2.72 | .262 | 1.05 | 7.1 | 2.4 | 9.8 | 182.0 | 143 | 60 | 55 | 15 | 49 | 199 | 5 | 0 | 0 | 2 | 20 | 2 | 3 | 2.73 |
| SP | Wainwright, A.Wainwright, Adam # >> | 31 | 2012 | R | 68 | 25 | 25 | 11 | 5 | 2.91 | .266 | 1.08 | 7.6 | 2.1 | 7.8 | 176.0 | 148 | 59 | 57 | 11 | 42 | 153 | 0 | 0 | 0 | 0 | 18 | 1 | 1 | 2.81 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 99 | 24 | 24 | 13 | 7 | 2.87 | .289 | 1.22 | 7.1 | 3.8 | 9.7 | 160.0 | 127 | 55 | 51 | 9 | 68 | 172 | 2 | 0 | 0 | 0 | 17 | 0 | 4 | 2.86 |
| SP | Bumgarner, M.Bumgarner, Madison † >> | 22 | 2012 | L | 93 | 26 | 26 | 14 | 7 | 2.78 | .263 | 1.06 | 7.7 | 1.9 | 7.2 | 187.2 | 159 | 67 | 58 | 15 | 39 | 150 | 3 | 0 | 0 | 2 | 18 | 3 | 5 | 3.11 |
| SP | Corbin, P.Corbin, Patrick # >> | 22 | 2012 | L | 45 | 22 | 22 | 7 | 2 | 4.09 | .303 | 1.28 | 10.2 | 1.4 | 7.1 | 116.2 | 131 | 56 | 53 | 12 | 18 | 91 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 3.32 |
| RP | Bowden, M.Bowden, Michael † >> | 26 | 2012 | R | 59 | 66 | 0 | 9 | 4 | 2.64 | .277 | 1.11 | 6.8 | 3.3 | 7.4 | 85.1 | 64 | 28 | 25 | 4 | 31 | 70 | 0 | 9 | 5 | 0 | 0 | 3 | 5 | 3.16 |
| RP | Coleman, L.Coleman, Louis >> | 26 | 2012 | R | 64 | 47 | 0 | 3 | 4 | 1.81 | .281 | 1.13 | 5.8 | 4.5 | 11.5 | 54.2 | 35 | 15 | 11 | 2 | 27 | 69 | 0 | 10 | 0 | 0 | 0 | 2 | 0 | 2.54 |
| RP | Hernandez, L.Hernandez, Livan >> | 37 | 2012 | R | 13 | 48 | 0 | 3 | 1 | 2.81 | .311 | 1.32 | 9.3 | 2.7 | 6.9 | 57.2 | 59 | 21 | 18 | 3 | 17 | 44 | 0 | 10 | 2 | 0 | 0 | 2 | 2 | 3.14 |
| SP | Chatwood, T.Chatwood, Tyler >> | 22 | 2012 | R | 9 | 4 | 2 | 0 | 0 | 5.73 | .353 | 1.64 | 9.8 | 4.9 | 2.5 | 11.0 | 12 | 7 | 7 | 0 | 6 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.09 |
| RP | Villarreal, B.Villarreal, Brayan >> | 25 | 2012 | R | 79 | 37 | 0 | 6 | 1 | 2.41 | .287 | 1.21 | 5.1 | 5.8 | 9.7 | 37.1 | 21 | 10 | 10 | 3 | 24 | 40 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 3.84 |